Anti-IFNGR1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IFNGR1 Antibody (CSB-PA011051DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

IFN-gamma receptor 1 Antibody,IFN-gamma-R1 Antibody,CDw119 Antibody,CD119 Antibody,IFNGR1 Antibody

More alternative names for the antibody
Antiviral Protein Type II antibody|Antiviral protein, type 2 antibody|AVP type II antibody|AVP, type 2 antibody|CD 119 antibody|CD119 antibody|CD119 antigen antibody|CDw119 antibody|FLJ45734 antibody|IFN gamma R alpha antibody|IFN gamma R antibody|IFN gamma R1 antibody|IFN-gamma receptor 1 antibody|IFN-gamma-R1 antibody|IFNG R1 antibody|IFNGR 1 antibody|IFNGR antibody|IFNGR1 antibody|Immune interferon receptor 1 antibody|Immune interferon receptor for antibody|INGR1_HUMAN antibody|Interferon gamma receptor 1 antibody|Interferon gamma receptor alpha chain antibody|Interferon gamma receptor alpha chain precursor antibody
Anti-IFNGR1 antibody (ab61179)
Close sc-74450|sc-12755|sc-703|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-IFNGR1 Antibody

Catalogue No.

CSB-PA011051DSR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Interferon gamma receptor 1 protein (270-489AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

54 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3459( Human), Entrez Gene:15979( Mouse), Omim:107470( Human), SwissProt:P15260( Human), SwissProt:P15261( Mouse), Unigene:520414( Human), Unigene:549( Mouse)

Protein function

Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). .

Involvement in disease

Immunodeficiency 27A (IMD27A) [MIM:209950]: A form of Mendelian susceptibility to mycobacterial disease, a rare condition caused by impairment of interferon-gamma mediated immunity. It is characterized by predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine, environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. Clinical outcome severity depends on the degree of impairment of interferon-gamma mediated immunity. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Immunodeficiency 27B (IMD27B) [MIM:615978]: A form of Mendelian susceptibility to mycobacterial disease, a rare condition caused by impairment of interferon-gamma mediated immunity. It is characterized by predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine, environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. Clinical outcome severity depends on the degree of impairment of interferon-gamma mediated immunity. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. IMD27B commonly presents with recurrent, moderately severe infections with environmental mycobacteria or BCG. Salmonellosis is present in about 5% of patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the type II cytokine receptor family.

Protein post-translational modifications

Phosphorylated at Ser/Thr residues. .

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein .

Research area

All research areas>Membrane Receptors>Interferon Receptor
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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