Anti-IFNLR1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IFNLR1 Antibody (CSB-PA816871ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Interferon lambda receptor 1 Antibody,IFN-lambda receptor 1 Antibody,IFN-lambda-R1 Antibody,Cytokine receptor class-II member 12 Antibody,Cytokine receptor family 2 member 12 Antibody,CRF2-12 Antibody,Interleukin-28 receptor subunit alpha Antibody,IL-28 receptor subunit alpha Antibody,IL-28R-alpha Antibody,IL-28RA Antibody,Likely interleukin or cytokine receptor 2 Antibody,LICR2 Antibody,IFNLR1 Antibody,IL28RA Antibody,LICR2 Antibody

More alternative names for the antibody

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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-IFNLR1 Antibody

Catalogue No.

CSB-PA816871ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Interferon lambda receptor 1 protein (21-228AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

Belongs to the type II cytokine receptor family.

Protein cellular localization

Membrane ; Single-pass type I membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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