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Rabbit Anti-IFNLR1 Antibody (CSB-PA816871ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Interferon lambda receptor 1 Antibody,IFN-lambda receptor 1 Antibody,IFN-lambda-R1 Antibody,Cytokine receptor class-II member 12 Antibody,Cytokine receptor family 2 member 12 Antibody,CRF2-12 Antibody,Interleukin-28 receptor subunit alpha Antibody,IL-28 receptor subunit alpha Antibody,IL-28R-alpha Antibody,IL-28RA Antibody,Likely interleukin or cytokine receptor 2 Antibody,LICR2 Antibody,IFNLR1 Antibody,IL28RA Antibody,LICR2 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Interferon lambda receptor 1 protein (21-228AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. .
|Protein tissue specificity|| |
Widely expressed. .
|Protein sequence and domain|| |
Belongs to the type II cytokine receptor family.
|Protein cellular localization|| |
Membrane ; Single-pass type I membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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