Anti-IFT57 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IFT57 Antibody (CSB-PA865156ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Dermal papilla-derived protein 8 Antibody,Estrogen-related receptor beta-like protein 1 Antibody,HIP1-interacting protein Antibody,MHS4R2 Antibody,IFT57 Antibody,DERP8 Antibody, ESRRBL1 Antibody,HIPPI Antibody

More alternative names for the antibody
CDNA FLJ10147 fis clone HEMBA1003369 antibody|
Anti-HIPPI antibody (ab5205)
Close sc-390120|sc-130456|sc-21995|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-IFT57 Antibody

Catalogue No.

CSB-PA865156ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Intraflagellar transport protein 57 homolog protein (170-429AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

49 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:55081( Human), Entrez Gene:73916( Mouse), Omim:606621( Human), SwissProt:Q9NWB7( Human), SwissProt:Q8BXG3( Mouse), Unigene:412196( Human), Unigene:241276( Mouse), Unigene:404371( Mouse)

Protein function

Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. .

Protein tissue specificity

Present in many tissues such as brain, thymus, lymph node, lung, liver, skin and kidney (at protein level). .

Protein sequence and domain

Belongs to the IFT57 family. The pseudo DED region (pDED) meadiates the interaction with HIP1.

Protein cellular localization

Cytoplasm, cytoskeleton, cilium basal body . Note=Concentrates within the inner segment of cilia. .

Research area

All research areas>Neurobiology Antibodies>Hippi
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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