Anti-IKZF3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IKZF3 Antibody (CSB-PA892336DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ikaros family zinc finger protein 3 Antibody,IKZF3 Antibody,ZNFN1A3 Antibody

More alternative names for the antibody
AIO antibody|Aiolos antibody|IKAROS family zinc finger 3 (Aiolos) antibody|IKAROS family zinc finger 3 antibody|Ikaros family zinc finger protein 3 antibody|IKZF 3 antibody|IKZF3 antibody|IKZF3_HUMAN antibody|zinc finger DNA binding protein Aiolos antibody|Zinc finger protein Aiolos antibody|Zinc finger protein subfamily 1A 3 (Aiolos) antibody|Zinc finger protein subfamily 1A 3 antibody|Zinc finger protein subfamily 1A, member 3 antibody|ZNFN1A3 antibody
Anti-IKZF3 antibody [EPR9342(B)] (ab139408)
Close sc-101982|sc-160013|

Recommended applications: ELISA, WB

Recommended dilution: Recommended dilution:WB:1:200-1000

Recommended protocols: check protocols

Name

Anti-IKZF3 Antibody

Catalogue No.

CSB-PA892336DSR1HU

Reactivity

Human

Immunogen

Recombinant human Zinc finger protein Aiolos protein (280-450AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

Recommended dilution:WB:1:200-1000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

58 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:22806( Human), Entrez Gene:22780( Mouse), Entrez Gene:303511( Rat), Omim:606221( Human), SwissProt:Q9UKT9( Human), SwissProt:O08900( Mouse), Unigene:371680( Human), Unigene:444388( Human), Unigene:133367( Mouse), Unigene:459157( Mouse), Unigene:218596( Rat)

Protein function

Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. .

Protein tissue specificity

Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. .

Protein sequence and domain

Belongs to the Ikaros C2H2-type zinc-finger protein family.

Protein post-translational modifications

Phosphorylation on tyrosine residues induced by IL2 is required for dissociation from HRAS and nuclear translocation of IKZF3 in T-cells. Phosphorylation on tyrosine residues induced by IL4 is required for dissociation from Bcl-X(L) in T-cells. .

Protein cellular localization

Nucleus. Cytoplasm.

Research area

All research areas>Transcription Regulators>Aiolos
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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