Anti-IL1R1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IL1R1 Antibody (CSB-PA011621ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

IL-1R-1 Antibody,IL-1RT-1 Antibody,IL-1RT1 Antibody,CD121 antigen-like family member A Antibody,Interleukin-1 receptor alpha Antibody,IL-1R-alpha Antibody,Interleukin-1 receptor type I Antibody,p80 Antibody,IL1R1 Antibody,IL1R Antibody, IL1RA Antibody, IL1RT1 Antibody

More alternative names for the antibody
Antigen CD121a antibody|CD121 antigen-like family member A antibody|CD121a antibody|CD121a antigen antibody|D2S1473 antibody|IL 1 antibody|IL 1R 1 antibody|IL 1R alpha antibody|IL 1RT1 antibody|IL-1R-1 antibody|IL-1R-alpha antibody|IL-1RT-1 antibody|IL-1RT1 antibody|IL1 inhibitor antibody|IL1R antibody|IL1R1 antibody|IL1R1_HUMAN antibody|IL1RA antibody|IL1RN antibody|IL1RT1 antibody|Interleukin 1 receptor alpha type 1 antibody|Interleukin 1 receptor antagonist protein (IRAP) antibody|Interleukin 1 receptor type I antibody|Interleukin receptor 1 antibody|Interleukin-1 receptor alpha antibody|Interleukin-1 receptor type 1 antibody|Interleukin-1 receptor type I antibody|p80 antibody
Anti-IL1 Receptor I antibody (ab106278)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-IL1R1 Antibody

Catalogue No.

CSB-PA011621ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Interleukin-1 receptor type 1 protein (18-320AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

65 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3554( Human), Entrez Gene:16177( Mouse), Entrez Gene:25663( Rat), Omim:147810( Human), SwissProt:P14778( Human), SwissProt:P13504( Mouse), SwissProt:Q02955( Rat), Unigene:701982( Human), Unigene:896( Mouse), Unigene:9758( Rat)

Protein function

Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. .

Protein sequence and domain

Belongs to the interleukin-1 receptor family.

Protein post-translational modifications

A soluble form (sIL1R1) is probably produced by proteolytic cleavage at the cell surface (shedding). .; Rapidly phosphorylated on Tyr-496 in response to IL-1, which creates a SH2 binding site for the PI 3-kinase regulatory subunit PIK3R1. .

Protein cellular localization

Membrane ; Single-pass type I membrane protein . Cell membrane . Secreted .

Research area

All research areas>Membrane Receptors>IL-1R
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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