Anti-IL21R Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IL21R Antibody (CSB-PA862061ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Interleukin-21 receptor Antibody,IL-21 receptor Antibody,IL-21R Antibody,Novel interleukin receptor Antibody,CD360 Antibody,IL21R Antibody,NILR Antibody,UNQ3121/PRO10273 Antibody

More alternative names for the antibody
CD360 antibody|IL 21R antibody|IL-21 receptor antibody|IL-21R antibody|IL21 receptor antibody|IL21R antibody|IL21R_HUMAN antibody|Interleukin 21 receptor antibody|Interleukin-21 receptor antibody|MGC10967 antibody|NILR antibody|Novel interleukin receptor antibody
Anti-IL21 Receptor antibody (ab13268)
Close sc-515062|sc-137120|sc-32902|sc-23075|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-IL21R Antibody

Catalogue No.

CSB-PA862061ESR2HU

Reactivity

Human

Immunogen

Recombinant human Interleukin-21 receptor protein (20-240AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

59 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:50615( Human), Entrez Gene:60504( Mouse), Entrez Gene:308977( Rat), Omim:605383( Human), SwissProt:Q9HBE5( Human), SwissProt:Q9JHX3( Mouse), Unigene:210546( Human), Unigene:155643( Mouse)

Protein function

This is a receptor for interleukin-21.

Protein tissue specificity

Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.

Involvement in disease

IL21R immunodeficiency (IL21RID) [MIM:615207]: An autosomal recessive primary immunodeficiency characterized by B- and T-cell defects and variable dysfunction of NK cells. Patients tend to have normal numbers of lymphocytes, but show defective class-switched B-cells, low IgG, defective antibody response, and defective T-cell responses to certain antigens. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Note=Chromosomal aberrations involving IL21R is a cause of B-cell non-Hodgkin lymphomas (B-cell NHL). Translocation t(3;16)(q27;p11), with BCL6.

Protein sequence and domain

Belongs to the type I cytokine receptor family. Type 4 subfamily. The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.; The box 1 motif is required for JAK interaction and/or activation.

Protein post-translational modifications

C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Membrane Receptors>IL-21R
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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