Anti-IL22RA1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-IL22RA1 Antibody (CSB-PA822717ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

IL-22 receptor subunit alpha-1 Antibody,IL-22R-alpha-1 Antibody,IL-22RA1 Antibody,Cytokine receptor class-II member 9 Antibody,Cytokine receptor family 2 member 9 Antibody,CRF2-9 Antibody,ZcytoR11 Antibody,IL22RA1 Antibody,IL22R Antibody

More alternative names for the antibody
CRF2 9 antibody|CRF2-9 antibody|Cytokine receptor class-II member 9 antibody|cytokine receptor classII member 9 antibody|Cytokine receptor family 2 member 9 antibody|I22R1_HUMAN antibody|IL-22 receptor subunit alpha-1 antibody|IL-22R-alpha-1 antibody|IL-22RA1 antibody|IL22R antibody|IL22R1 antibody|Il22ra1 antibody|ILTIF R1 chain antibody|Interleukin 22 Receptor alpha 1 antibody|Interleukin 22 Receptor antibody|Interleukin-22 receptor subunit alpha-1 antibody|ZcytoR11 antibody
Anti-IL22 Receptor Alpha antibody (ab5984)
Close sc-168172|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-IL22RA1 Antibody

Catalogue No.

CSB-PA822717ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Interleukin-22 receptor subunit alpha-1 protein (16-230AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

63 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:58985( Human), Entrez Gene:230828( Mouse), Omim:605457( Human), SwissProt:Q8N6P7( Human), SwissProt:Q80XZ4( Mouse), Unigene:110915( Human), Unigene:261647( Mouse)

Protein function

Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. .

Protein tissue specificity

Expressed in colon, liver, lung, pancreas and kidney. No expression in immune cells such as monocytes, T-cells, and NK-cells. Expressed in keratinocytes of normal skin as well as in psoriatic skin lesion. Detected in normal blood brain barrier endothelial cells as well as in multiple sclerosis lesions; Strongly expressed on central nervous system vessels within infiltrated multiple sclerosis lesions. Overexpressed in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. .

Protein sequence and domain

Belongs to the type II cytokine receptor family.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Membrane Receptors>IL-22R
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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