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Rabbit Anti-IL22RA1 Antibody (CSB-PA822717ESR2HU)
Supplier: CUSABIO BIOTECH CO.
IL-22 receptor subunit alpha-1 Antibody,IL-22R-alpha-1 Antibody,IL-22RA1 Antibody,Cytokine receptor class-II member 9 Antibody,Cytokine receptor family 2 member 9 Antibody,CRF2-9 Antibody,ZcytoR11 Antibody,IL22RA1 Antibody,IL22R AntibodyMore alternative names for the antibody
CRF2 9 antibody|CRF2-9 antibody|Cytokine receptor class-II member 9 antibody|cytokine receptor classII member 9 antibody|Cytokine receptor family 2 member 9 antibody|I22R1_HUMAN antibody|IL-22 receptor subunit alpha-1 antibody|IL-22R-alpha-1 antibody|IL-22RA1 antibody|IL22R antibody|IL22R1 antibody|Il22ra1 antibody|ILTIF R1 chain antibody|Interleukin 22 Receptor alpha 1 antibody|Interleukin 22 Receptor antibody|Interleukin-22 receptor subunit alpha-1 antibody|ZcytoR11 antibody
Anti-IL22 Receptor Alpha antibody (ab5984)
Anti-IL22 Receptor Alpha antibody (ab5984)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Interleukin-22 receptor subunit alpha-1 protein (16-230AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=58985" target="_blank">Entrez Gene:58985( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=230828" target="_blank">Entrez Gene:230828( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/605457" target="_blank">Omim:605457( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q8N6P7" target="_blank">SwissProt:Q8N6P7( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q80XZ4" target="_blank">SwissProt:Q80XZ4( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=110915" target="_blank">Unigene:110915( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=261647" target="_blank">Unigene:261647( Mouse)</a>
|Protein function|| |
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. .
|Protein tissue specificity|| |
Expressed in colon, liver, lung, pancreas and kidney. No expression in immune cells such as monocytes, T-cells, and NK-cells. Expressed in keratinocytes of normal skin as well as in psoriatic skin lesion. Detected in normal blood brain barrier endothelial cells as well as in multiple sclerosis lesions; Strongly expressed on central nervous system vessels within infiltrated multiple sclerosis lesions. Overexpressed in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. .
|Protein sequence and domain|| |
Belongs to the type II cytokine receptor family.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Membrane-Receptors/">Membrane Receptors</a>><a href="https://antibodyplus.com/product-tag/IL-22R/">IL-22R</a><br><a href="https://antibodyplus.com/product-tag/Membrane-Receptors/"> (View all antibody categories related to Membrane Receptors)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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