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Rabbit Anti-ILF3 Antibody (CSB-PA613273ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Double-stranded RNA-binding protein 76 Antibody,DRBP76 Antibody,M-phase phosphoprotein 4 Antibody,MPP4 Antibody,Nuclear factor associated with dsRNA Antibody,NFAR Antibody,Nuclear factor of activated T-cells 90 kDa Antibody,NF-AT-90 Antibody,Translational control protein 80 Antibody,TCP80 AntibodyMore alternative names for the antibody
CBTF antibody|Double stranded RNA binding protein 76 antibody|Double-stranded RNA-binding protein 76 antibody|DRBF antibody|DRBP76 antibody|ILF3 antibody|ILF3_HUMAN antibody|Interleukin enhancer binding factor 3 antibody|Interleukin enhancer-binding factor 3 antibody|M phase phosphoprotein 4 antibody|M-phase phosphoprotein 4 antibody|MPHOSPH4 antibody|MPP4 antibody|NF AT 90 antibody|NF-AT-90 antibody|NF110 antibody|NF90 antibody|NFAR antibody|Nuclear factor associated with dsRNA antibody|Nuclear factor of activated T cells 90 kDa antibody|Nuclear factor of activated T-cells 90 kDa antibody|TCP80 antibody|Translational control protein 80 antibody
Anti-ILF3 antibody [EPR3626] (ab92355)
Anti-ILF3 antibody [EPR3626] (ab92355)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Interleukin enhancer-binding factor 3 protein (785-894AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3609" target="_blank">Entrez Gene:3609( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=16201" target="_blank">Entrez Gene:16201( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/603182" target="_blank">Omim:603182( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q12906" target="_blank">SwissProt:Q12906( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q9Z1X4" target="_blank">SwissProt:Q9Z1X4( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=465885" target="_blank">Unigene:465885( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=440026" target="_blank">Unigene:440026( Mouse)</a>
|Protein function|| |
May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. The phosphorylated form at Thr-188 and Thr-315, in concert with EIF2AK2/PKR can inhibit vesicular stomatitis virus (VSV) replication (By similarity). .
|Protein tissue specificity|| |
|Protein post-translational modifications|| |
Phosphorylated at Thr-188 and Thr-315 by PKR in response to certain RNA viruses. This phosphorylation results in the dissociation of ILF2 from the ILF2-ILF3 complex resulting in a cytoplasmic sequestration of ILF3 where it can bind to viral RNAs and impede viral replication. .; Methylated by protein arginine N-methyltransferase 1.; Arg-609 is dimethylated, probably to asymmetric dimethylarginine.
|Protein cellular localization|| |
Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in response to viral dsRNA. The unphosphorylated form is retained in the nucleus by ILF2. Phosphorylation at Thr-188 and Thr-315 causes the dissociation of ILF2 from the ILF2-ILF3 complex resulting in a cytoplasmic sequestration of ILF3. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="https://antibodyplus.com/product-tag/NF90/">NF90</a><br><a href="https://antibodyplus.com/product-tag/Transcription-Regulators/"> (View all antibody categories related to Transcription Regulators)</a>
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|Product type|| |
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