Anti-KCNS3 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-KCNS3 Antibody (CSB-PA859028ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Potassium voltage-gated channel subfamily S member 3 Antibody,Delayed-rectifier K(+) channel alpha subunit 3 Antibody,Voltage-gated potassium channel subunit Kv9.3 Antibody,KCNS3 Antibody

More alternative names for the antibody
Delayed rectifier K(+) channel alpha subunit 3 antibody|Voltage gated potassium channel subunit Kv9.3 antibody|Voltage-gated potassium channel subunit Kv9.3 antibody
Anti-KCNS3 antibody (ab26164)
Close sc-365497|sc-365979|

Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-KCNS3 Antibody

Catalogue No.

CSB-PA859028ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Potassium voltage-gated channel subfamily S member 3 protein (1-180AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

56 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3790( Human), Entrez Gene:238076( Mouse), Entrez Gene:83588( Rat), Omim:603888( Human), SwissProt:Q9BQ31( Human), SwissProt:Q8BQZ8( Mouse), SwissProt:O88759( Rat), Unigene:414489( Human), Unigene:113278( Mouse), Unigene:10878( Rat)

Protein function

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:10484328). Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (By similarity). .

Protein tissue specificity

Detected in whole normal term placental and placental chorionic plate arteries and veins. Detected in syncytiotrophoblast and in blood vessel endothelium within intermediate villi and chorionic plate (at protein level) (PubMed:22943705). Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung (PubMed:10484328). .

Protein sequence and domain

Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily. The transmembrane segment S4 functions as voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Channel opening and closing is effected by a conformation change that affects the position and orientation of the voltage-sensor paddle formed by S3 and S4 within the membrane. A transmembrane electric field that is positive inside would push the positively charged S4 segment outwards, thereby opening the pore, while a field that is negative inside would pull the S4 segment inwards and close the pore. Changes in the position and orientation of S4 are then transmitted to the activation gate formed by the inner helix bundle via the S4-S5 linker region.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328). .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!