Anti-KERA Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-KERA Antibody (CSB-PA012149ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Keratocan Antibody,KTN Antibody,Keratan sulfate proteoglycan keratocan Antibody,KERA Antibody,SLRR2B Antibody

More alternative names for the antibody
CNA2 antibody|KERA antibody|KERA_HUMAN antibody|Keratan sulfate proteoglycan keratocan antibody|Keratocan antibody|KTN antibody|SLRR2B antibody
Anti-Keratocan antibody (ab113115)
Close sc-33243|sc-33242|sc-66941|sc-33244|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-KERA Antibody

Catalogue No.

CSB-PA012149ESR1HU

Reactivity

Human

Immunogen

Recombinant human Keratocan protein (21-352AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

40 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:11081( Human), Omim:603288( Human), SwissProt:O60938( Human), Unigene:125750( Human)

Protein function

May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.

Protein tissue specificity

Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen. .

Involvement in disease

Cornea plana 2, autosomal recessive (CNA2) [MIM:217300]: A severe form of cornea plana, a rare ocular disorder characterized by flattened corneal curvature leading to a decrease in refraction, reduced visual activity, hyperopia, hazy corneal limbus, opacities in the corneal parenchyma, and marked arcus senilis often detected at an early age. CNA2 patients manifest extreme hyperopia and additional ocular anomalies such as malformations of the iris, a slit-like pupil, and adhesions between iris and cornea. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.

Protein post-translational modifications

Binds keratan sulfate chains. .

Protein cellular localization

Secreted, extracellular space, extracellular matrix .

Research area

All research areas>Signaling Intermediates>Keratocan
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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