Anti-KIF1B Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-KIF1B Antibody (CSB-PA012319ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Kinesin-like protein KIF1B Antibody,Klp Antibody,KIF1B Antibody,KIAA0591 Antibody,KIAA1448 Antibody

More alternative names for the antibody
Charcot Marie Tooth neuropathy 2A antibody|CMT 2 antibody|CMT 2A antibody|CMT 2A1 antibody|CMT2 A antibody|CMT2 A1 antibody|CMT2 antibody|CMT2A 1 antibody|CMT2A antibody|CMT2A1 antibody|D4Mil1e antibody|HMSN II antibody|HMSNII antibody|HMSNII, hereditary motor sensory neuropathy II antibody|KIF 1B antibody|KIF1 B antibody|KIF1B p130 antibody|KIF1B p204 antibody|KIF1Bp130 antibody|KIF1Bp204 antibody|kinesin family member 1B antibody|Kinesin like protein KIF1B antibody|Klp antibody
Anti-KIF1B antibody (ab69614)
Close sc-376246|sc-28540|sc-18739|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-KIF1B Antibody

Catalogue No.

CSB-PA012319ESR1HU

Reactivity

Human

Immunogen

Recombinant human Kinesin-like protein KIF1B protein (1547-1816AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

204 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23095( Human), Entrez Gene:16561( Mouse), Entrez Gene:117548( Rat), Omim:605995( Human), SwissProt:O60333( Human), SwissProt:Q60575( Mouse), SwissProt:O88658( Rat), Unigene:97858( Human), Unigene:402393( Mouse)

Protein function

Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. .

Protein tissue specificity

Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas. .

Involvement in disease

Charcot-Marie-Tooth disease 2A1 (CMT2A1) [MIM:118210]: A dominant axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Neuroblastoma 1 (NBLST1) [MIM:256700]: A common neoplasm of early childhood arising from embryonic cells that form the primitive neural crest and give rise to the adrenal medulla and the sympathetic nervous system. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; Pheochromocytoma (PCC) [MIM:171300]: A catecholamine-producing tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

Protein cellular localization

Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Mitochondrion . Note=Colocalizes with synaptophysin at synaptic cytoplasmic transport vesicles in the neurites of hippocampal neurons. .

Research area

All research areas>Structural Proteins>KIF
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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