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Rabbit Anti-KIF1B Antibody (CSB-PA012319ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Kinesin-like protein KIF1B Antibody,Klp Antibody,KIF1B Antibody,KIAA0591 Antibody,KIAA1448 AntibodyMore alternative names for the antibody
Charcot Marie Tooth neuropathy 2A antibody|CMT 2 antibody|CMT 2A antibody|CMT 2A1 antibody|CMT2 A antibody|CMT2 A1 antibody|CMT2 antibody|CMT2A 1 antibody|CMT2A antibody|CMT2A1 antibody|D4Mil1e antibody|HMSN II antibody|HMSNII antibody|HMSNII, hereditary motor sensory neuropathy II antibody|KIF 1B antibody|KIF1 B antibody|KIF1B p130 antibody|KIF1B p204 antibody|KIF1Bp130 antibody|KIF1Bp204 antibody|kinesin family member 1B antibody|Kinesin like protein KIF1B antibody|Klp antibody
Anti-KIF1B antibody (ab69614)
Anti-KIF1B antibody (ab69614)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Kinesin-like protein KIF1B protein (1547-1816AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:23095( Human), Entrez Gene:16561( Mouse), Entrez Gene:117548( Rat), Omim:605995( Human), SwissProt:O60333( Human), SwissProt:Q60575( Mouse), SwissProt:O88658( Rat), Unigene:97858( Human), Unigene:402393( Mouse)
|Protein function|| |
Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. .
|Protein tissue specificity|| |
Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas. .
|Involvement in disease|| |
Charcot-Marie-Tooth disease 2A1 (CMT2A1) [MIM:118210]: A dominant axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Neuroblastoma 1 (NBLST1) [MIM:256700]: A common neoplasm of early childhood arising from embryonic cells that form the primitive neural crest and give rise to the adrenal medulla and the sympathetic nervous system. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.; Pheochromocytoma (PCC) [MIM:171300]: A catecholamine-producing tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.
|Protein cellular localization|| |
Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Mitochondrion . Note=Colocalizes with synaptophysin at synaptic cytoplasmic transport vesicles in the neurites of hippocampal neurons. .
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CUSABIO BIOTECH CO.
|Product type|| |
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