Anti-KITLG Antibody


Reactivity: Human
Applications: ELISA,WB
Conjugation: Various

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-KITLG Antibody (CSB-PA012376ESR2HU)


Alternative names:

Mast cell growth factor Antibody,MGF Antibody,Stem cell factor Antibody,SCF Antibody,c-Kit ligand Antibody,sKITLG Antibody,KITLG Antibody,MGF Antibody, SCF Antibody

More alternative names for the antibody
C kit ligand antibody|C-kit ligand antibody|Ckit ligand antibody|DCUA antibody|DFNA69 antibody|DKFZp686F2250 antibody|familial progressive hyperpigmentation 2 antibody|FPH2 antibody|FPHH antibody|KIT ligand antibody|Kitl antibody|KITLG antibody|KL 1 antibody|KL1 antibody|Mast cell growth factor antibody|MGF antibody|MGF stem cell factor antibody|SCF antibody|SCF_HUMAN antibody|SF antibody|SHEP7 antibody|sKITLG antibody|Soluble KIT ligand antibody|Steel factor antibody|steel, mouse, homolog of antibody|Stem cell factor antibody|Stem cell factor precursor antibody
Anti-SCF antibody (ab64677)

Recommended applications: ELISA, WB

Recommended dilution: Recommended dilution:WB:1:500-2000

Recommended protocols: check protocols


Anti-KITLG Antibody

Catalogue No.





Recombinant human Kit ligand protein (26-214AA)





Recommended dilution

Recommended dilution:WB:1:500-2000







Molecular weight

30 kDa


Antigen Affinity Purified


Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4254( Human), Entrez Gene:17311( Mouse), Entrez Gene:60427( Rat), Omim:184745( Human), SwissProt:P21583( Human), SwissProt:P20826( Mouse), SwissProt:P21581( Rat), Unigene:1048( Human), Unigene:661108( Human), Unigene:45124( Mouse), Unigene:44216( Rat)

Protein function

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Involvement in disease

Hyperpigmentation with or without hypopigmentation, familial progressive (FPHH) [MIM:145250]: A disorder characterized by hyperpigmented patches in the skin, present in early infancy and increasing in size and number with age. Hyperpigmentation has variable intensity, and sometimes is associated with cafe-au-lait macules and larger hypopigmented ash-leaf macules. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Deafness, congenital, unilateral or asymmetric (DCUA) [MIM:616697]: An autosomal dominant form of non-syndromic, sensorineural deafness characterized by inability to hear affecting one ear. Some patients suffers from asymmetric, bilateral hearing loss. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the SCF family.

Protein post-translational modifications

A soluble form (sKITLG) is produced by proteolytic processing of isoform 1 in the extracellular domain. .; Found in two differentially glycosylated forms, LMW-SCF and HMW-SCF. LMW-SCF is fully N-glycosylated at Asn-145, partially N-glycosylated at Asn-90, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97 or Asn-118. HMW-SCF is N-glycosylated at Asn-118, Asn-90 and Asn-145, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97. .; A soluble form exists as a cleavage product of the extracellular domain. .

Protein cellular localization

Isoform 1: Cell membrane; Single-pass type I membrane protein.; Isoform 2: Cytoplasm . Cytoplasm, cytoskeleton . Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium . Cell projection, filopodium .; Soluble KIT ligand: Secreted.


AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.



Product type

Primary antibody


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!