Anti-KPNA6 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-KPNA6 Antibody (CSB-PA012488ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Importin subunit alpha-7 Antibody,Karyopherin subunit alpha-6 Antibody,KPNA6 Antibody,IPOA7 Antibody

More alternative names for the antibody
FLJ11249 antibody|IMA7_HUMAN antibody|Importin alpha 7 subunit antibody|Importin alpha S2 antibody|Importin subunit alpha 7 antibody|Importin subunit alpha-7 antibody|IPOA 7 antibody|IPOA7 antibody|Karyopherin alpha 6 antibody|Karyopherin alpha 6 (importin alpha 7) antibody|Karyopherin subunit alpha 6 antibody|Karyopherin subunit alpha-6 antibody|KPNA 6 antibody|KPNA 7 antibody|Kpna6 antibody|KPNA7 antibody|MGC17918 antibody|OTTHUMP00000004532 antibody
Anti-KPNA6 antibody (ab110016)
Close sc-68197|sc-390055|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-KPNA6 Antibody

Catalogue No.

CSB-PA012488ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Importin subunit alpha-7 protein (277-536AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

60 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23633( Human), Entrez Gene:16650( Mouse), Entrez Gene:362607( Rat), Omim:610563( Human), SwissProt:Q0V7M0( Cow), SwissProt:O60684( Human), SwissProt:O35345( Mouse), Unigene:470588( Human), Unigene:711019( Human), Unigene:202358( Mouse), Unigene:139167( Rat)

Protein function

Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

Belongs to the importin alpha family.

Research area

All research areas>Transport and Trafficking>karyopherin
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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