Anti-KYNU Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-KYNU Antibody (CSB-PA621970ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Kynureninase Antibody,L-kynurenine hydrolase Antibody,KYNU Antibody

More alternative names for the antibody
kynU antibody|KYNU_HUMAN antibody|kynureninase (L-kynurenine hydrolase) antibody|Kynureninase antibody|L-kynurenine hydrolase antibody
Anti-L-Kynurenine Hydrolase antibody – C-terminal (ab135786)
Close sc-132732|sc-390360|sc-132733|

Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-KYNU Antibody

Catalogue No.

CSB-PA621970ESR2HU

Reactivity

Human

Immunogen

Recombinant human Kynureninase protein (1-307AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

52 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8942( Human), Omim:605197( Human), SwissProt:Q16719( Human), Unigene:470126( Human)

Protein function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.

Protein tissue specificity

Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas). Highest levels found in placenta, liver and lung. Expressed in all brain regions. .

Involvement in disease

Hydroxykynureninuria (HYXKY) [MIM:236800]: An inborn error of amino acid metabolism characterized by massive urinary excretion of large amounts of kynurenine, 3-hydroxykynurenine and xanthurenic acid. Affected individuals manifest renal tubular dysfunction, metabolic acidosis, psychomotor retardation, non-progressive encephalopathy, and muscular hypertonia. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the kynureninase family.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Synthesis and Degradation>kynureninase
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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