Anti-LAMTOR5 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-LAMTOR5 Antibody (CSB-PA010161ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ragulator complex protein LAMTOR5 Antibody,Hepatitis B virus X-interacting protein Antibody,HBV X-interacting protein Antibody,HBX-interacting protein Antibody,Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Antibody,LAMTOR5 Antibody,HBXIP Antibody,XIP Antibody

More alternative names for the antibody
HBV X interacting protein antibody|HBV X-interacting protein antibody|HBX interacting protein antibody|HBX-interacting protein antibody|hbxip antibody|HBXIP_HUMAN antibody|Hepatitis B virus X interacting protein antibody|Hepatitis B virus X-interacting protein antibody|LAMTOR5 antibody|Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody|MGC71071 antibody|Ragulator complex protein LAMTOR5 antibody|XIP antibody
Anti-HBXIP antibody [EPR11531(B)] (ab157480)
Close sc-54080|sc-134791|sc-373980|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-LAMTOR5 Antibody

Catalogue No.

CSB-PA010161ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ragulator complex protein LAMTOR5 protein (1-173AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

9 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10542( Human), Entrez Gene:68576( Mouse), Entrez Gene:295357( Rat), Omim:608521( Human), SwissProt:O43504( Human), SwissProt:Q9D1L9( Mouse), Unigene:439815( Human)

Protein function

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. .

Protein tissue specificity

Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.

Protein sequence and domain

Belongs to the LAMTOR5 family.

Protein cellular localization

Cytoplasm. Lysosome.

Research area

All research areas>Tumor Suppressor/Apoptosis>HBXIP
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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