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Rabbit Anti-LDB3 Antibody (CSB-PA012831ESR2HU)
Supplier: CUSABIO BIOTECH CO.
LIM domain-binding protein 3 Antibody,Protein cypher Antibody,Z-band alternatively spliced PDZ-motif protein Antibody,LDB3 AntibodyMore alternative names for the antibody
CMD1C antibody|CYPHER antibody|HGNC:15710 antibody|KIAA01613 antibody|KIAA0613 antibody|Ldb3 antibody|LDB3_HUMAN antibody|LDB3Z1 antibody|LDB3Z4 antibody|LIM domain binding 3 antibody|LIM domain binding protein 3 antibody|LIM domain-binding protein 3 antibody|LVNC3 antibody|ORACLE antibody|PDLIM6 antibody|PDZ and LIM domain 6 antibody|Protein cypher antibody|Z band alternatively spliced PDZ motif antibody|Z band alternatively spliced PDZ motif protein antibody|Z-band alternatively spliced PDZ-motif protein antibody|ZASP antibody
Anti-LDB3 antibody [EPR10127] (ab154183)
Anti-LDB3 antibody [EPR10127] (ab154183)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human LIM domain-binding protein 3 protein (1-283AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:11155( Human), Entrez Gene:24131( Mouse), Entrez Gene:498587( Rat), Omim:605906( Human), SwissProt:O75112( Human), SwissProt:Q9JKS4( Mouse), Unigene:657271( Human), Unigene:29733( Mouse), Unigene:17340( Rat)
|Protein function|| |
May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton. .
|Protein tissue specificity|| |
Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta. .
|Involvement in disease|| |
Cardiomyopathy, dilated 1C, with or without left ventricular non-compaction (CMD1C) [MIM:601493]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Cardiomyopathy dilated type 1C is associated with left ventricular non-compaction in some patients. Left ventricular non-compaction is characterized by numerous prominent trabeculations and deep intertrabecular recesses in hypertrophied and hypokinetic segments of the left ventricle. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Left ventricular non-compaction 3 (LVNC3) [MIM:601493]: A disease due to an arrest of myocardial morphogenesis. It is characterized by a hypertrophic left ventricle with deep trabeculations and with poor systolic function, with or without associated left ventricular dilation. In some cases, it is associated with other congenital heart anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.; Myopathy, myofibrillar, 4 (MFM4) [MIM:609452]: A form of myofibrillar myopathy, a group of chronic neuromuscular disorders characterized at ultrastructural level by disintegration of the sarcomeric Z disc and myofibrils, and replacement of the normal myofibrillar markings by small dense granules, or larger hyaline masses, or amorphous material. MFM4 is characterized by distal and proximal muscle weakness with signs of cardiomyopathy and neuropathy. Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein cellular localization|| |
Cytoplasm, perinuclear region . Cell projection, pseudopodium . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Note=Localized to the cytoplasm around nuclei and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2 at the Z-lines.
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CUSABIO BIOTECH CO.
|Product type|| |
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