Anti-LFNG Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-LFNG Antibody (CSB-PA839868ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Beta-1 Antibody,3-N-acetylglucosaminyltransferase lunatic fringe Antibody,O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Antibody,LFNG Antibody

More alternative names for the antibody
3-N-acetylglucosaminyltransferase lunatic fringe antibody|Beta-1 antibody|Beta-13-N-acetylglucosaminyltransferase lunatic fringe antibody|lfng antibody|LFNG_HUMAN antibody|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody|SCDO3 antibody
Anti-Lunatic Fringe antibody [EPR10391(B)] (ab151699)
Close sc-324092|sc-100756|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-LFNG Antibody

Catalogue No.

CSB-PA839868ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe protein (1-250AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

41 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3955( Human), Entrez Gene:16848( Mouse), Entrez Gene:170905( Rat), Omim:602576( Human), SwissProt:Q8NES3( Human), SwissProt:O09010( Mouse), SwissProt:Q924T4( Rat), Unigene:159142( Human), Unigene:12834( Mouse), Unigene:127809( Rat)

Protein function

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning (By similarity). .

Involvement in disease

Spondylocostal dysostosis 3, autosomal recessive (SCDO3) [MIM:609813]: A condition of variable severity associated with vertebral and rib segmentation defects. The main skeletal malformations include fusion of vertebrae, hemivertebrae, fusion of certain ribs, and other rib malformations. Deformity of the chest and spine (severe scoliosis, kyphoscoliosis and lordosis) is a natural consequence of the malformation and leads to a dwarf-like appearance. As the thorax is small, infants frequently have respiratory insufficiency and repeated respiratory infections resulting in life-threatening complications in the first year of life. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the glycosyltransferase 31 family.

Protein post-translational modifications

A soluble form may be derived from the membrane form by proteolytic processing. .

Protein cellular localization

Golgi apparatus membrane ; Single-pass type II membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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