Anti-LGALS8 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-LGALS8 Antibody (CSB-PA012894ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Galectin-8 Antibody,Gal-8 Antibody,Po66 carbohydrate-binding protein Antibody,Po66-CBP Antibody,Prostate carcinoma tumor antigen 1 Antibody,PCTA-1 Antibody,LGALS8 Antibody

More alternative names for the antibody
Gal 8 antibody|Gal-8 antibody|Gal8 antibody|Galectin-8 antibody|galectin-8g antibody|Lectin galactoside binding soluble 8 antibody|LEG8_HUMAN antibody|LGAL S8 antibody|Lgals8 antibody|PCTA 1 antibody|PCTA-1 antibody|PCTA1 antibody|Po66 carbohydrate binding protein antibody|Po66 carbohydrate-binding protein antibody|Po66 CBP antibody|Po66-CBP antibody|Prostate carcinoma tumor antigen 1 antibody
Anti-Galectin 8 antibody [EPR4857] (ab109519)
Close sc-377133|sc-10265|sc-28254|sc-30376|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-LGALS8 Antibody

Catalogue No.

CSB-PA012894ESR2HU

Reactivity

Human

Immunogen

Recombinant human Galectin-8 protein (20-317AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

35 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3964( Human), Omim:606099( Human), SwissProt:O00214( Human), Unigene:4082( Human), Unigene:708114( Human)

Protein function

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3′-O-sialylated and 3′-O-sulfated glycans (PubMed:21288902). .

Protein tissue specificity

Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.

Protein sequence and domain

Contains two homologous but distinct carbohydrate-binding domains.

Protein cellular localization

Cytoplasmic vesicle . Cytoplasm, cytosol .

Research area

All research areas>Tumor Suppressor/Apoptosis>galectin
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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