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Rabbit Anti-LINGO1 Antibody (CSB-PA839321ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Antibody,Leucine-rich repeat and immunoglobulin domain-containing protein 1 Antibody,Leucine-rich repeat neuronal protein 1 Antibody,Leucine-rich repeat neuronal protein 6A Antibody,LINGO1 Antibody,LERN1 Antibody,LRRN6A Antibody,UNQ201/PRO227 AntibodyMore alternative names for the antibody
FLJ14594 antibody|LERN 1 antibody|LERN1 antibody|Leucine rich repeat and Ig domain containing 1 antibody|Leucine rich repeat neuronal 6A antibody|Leucine rich repeat neuronal protein 1 antibody|Leucine rich repeat neuronal protein 6A antibody|Leucine-rich repeat and immunoglobilin domain-containing protein 1 antibody|Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 antibody|Leucine-rich repeat neuronal protein 1 antibody|Leucine-rich repeat neuronal protein 6A antibody|LIGO1_HUMAN antibody|Lingo 1 antibody|LINGO1 antibody|LRR and Ig domain containing Nogo Receptor interating protein antibody|Lrrn 6a antibody|Lrrn6a antibody|Lrrn6a protein antibody|MGC17422 antibody|Nogo Receptor interacting protein antibody|PRO227 antibody|UNQ201 antibody
Anti-Lingo1 antibody (ab23631)
Anti-Lingo1 antibody (ab23631)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein (42-240AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:415344( Chicken), Entrez Gene:84894( Human), Entrez Gene:235402( Mouse), Entrez Gene:315691( Rat), Omim:609791( Human), SwissProt:Q50L44( Chicken), SwissProt:Q96FE5( Human), SwissProt:Q9D1T0( Mouse), Unigene:656765( Human), Unigene:246605( Mouse)
|Protein function|| |
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity). .
|Protein tissue specificity|| |
Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients. .
|Protein sequence and domain|| |
The intracellular domain of LINGO1 interacts with MYT1L.
|Protein post-translational modifications|| |
N-glycosylated. Contains predominantly high-mannose glycans. .
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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