Anti-MAGEC2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MAGEC2 Antibody (CSB-PA887003DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cancer/testis antigen 10 Antibody,CT10;Hepatocellular carcinoma-associated antigen 587;MAGE-C2 antigen;MAGE-E1 antigen;MAGEC2 Antibody,HCA587; MAGEE1 Antibody

More alternative names for the antibody
Cancer testis antigen 10 antibody|Cancer/testis antigen 10 antibody|CT10 antibody|HCA587 antibody|Hepatocellular cancer antigen 587 antibody|Hepatocellular carcinoma associated antigen 587 antibody|Hepatocellular carcinoma-associated antigen 587 antibody|MAGC2_HUMAN antibody|MAGE C2 antigen antibody|MAGE E1 antigen antibody|MAGE family member C2 antibody|MAGE-C2 antigen antibody|MAGE-E1 antigen antibody|MAGEC2 antibody|Melanoma antigen family C 2 antibody|Melanoma antigen family C2 antibody|Melanoma antigen family E 1 cancer/testis specific antibody|Melanoma associated antigen C2 antibody|Melanoma-associated antigen C2 antibody|MGC13377 antibody
Anti-MAGEE1 antibody [EPR19064] (ab209667)
Close sc-68603|sc-68852|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MAGEC2 Antibody

Catalogue No.

CSB-PA887003DSR2HU

Reactivity

Human

Immunogen

Recombinant human Melanoma-associated antigen C2 protein (1-150AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

41 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:51438( Human), Omim:300468( Human), SwissProt:Q9UBF1( Human), Unigene:123536( Human)

Protein function

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. .

Protein tissue specificity

Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non-small cell lung cancer and liver cancer. In hepatocellular carcinoma, there is a inverse correlation between tumor differentiation and protein expression, i.e. the lower the differentiation, the higher percentage of expression. .

Protein cellular localization

Cytoplasm . Nucleus . Note=Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.

Research area

All research areas>Tumor Suppressor/Apoptosis>MAGE
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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