Anti-MAP2K3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MAP2K3 Antibody (CSB-PA013412ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MAP kinase kinase 3 Antibody,MAPKK 3 Antibody,MAPK/ERK kinase 3 Antibody,MEK 3 Antibody,Stress-activated protein kinase kinase 2 Antibody,SAPK kinase 2 Antibody,SAPKK-2 Antibody,SAPKK2 Antibody,MAP2K3 Antibody,MEK3 Antibody, MKK3 Antibody, PRKMK3 Antibody,SKK2 Antibody

More alternative names for the antibody
AW212142 antibody|dual specificity mitogen activated protein kinase kinase 3 antibody|Dual specificity mitogen-activated protein kinase kinase 3 antibody|MAP kinase kinase 3 antibody|map2k3 antibody|MAPK ERK kinase 3 antibody|MAPK/ERK kinase 3 antibody|MAPKK 3 antibody|MAPKK3 antibody|MEK 3 antibody|MEK3 antibody|Mitogen activated protein kinase kinase 3 antibody|MKK 3 antibody|MKK3 antibody|mMKK3b antibody|MP2K3_HUMAN antibody|PRKMK 3 antibody|PRKMK3 antibody|protein kinase, mitogen-activated, kinase 3 antibody|SAPK kinase 2 antibody|SAPKK 2 antibody|SAPKK2 antibody|Stress activated protein kinase kinase 2 antibody
Anti-MEK3 antibody [EPR17345-104] (ab195037)
Close sc-135985|sc-81474|sc-376627|sc-271779|sc-961|sc-959|sc-136982|sc-133230|sc-137106|sc-13069|sc-136314|sc-837|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MAP2K3 Antibody

Catalogue No.

CSB-PA013412ESR1HU

Reactivity

Human

Immunogen

Recombinant human Dual specificity mitogen-activated protein kinase kinase 3 protein (1-170AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

39 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5606( Human), Entrez Gene:26397( Mouse), Entrez Gene:303200( Rat), Omim:602315( Human), SwissProt:P46734( Human), SwissProt:O09110( Mouse), Unigene:514012( Human), Unigene:18494( Mouse), Unigene:100064( Rat)

Protein function

Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. .

Protein tissue specificity

Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

Involvement in disease

Note=Defects in MAP2K3 may be involved in colon cancer.

Protein sequence and domain

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

Protein post-translational modifications

Autophosphorylated. Phosphorylation on Ser-218 and Thr-222 by MAP kinase kinase kinases regulates positively the kinase activity (PubMed:8622669). Phosphorylated by TAOK2 (PubMed:11279118). .; Yersinia yopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway. .

Research area

All research areas>Kinases and Phosphatases>MEK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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