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Rabbit Anti-MAP2K5 Antibody (CSB-PA615667ESR2HU)
Supplier: CUSABIO BIOTECH CO.
MAP kinase kinase 5 Antibody,MAPKK 5 Antibody,MAPK/ERK kinase 5 Antibody,MEK 5 Antibody,MAP2K5 Antibody,MEK5 Antibody, MKK5 Antibody, PRKMK5 AntibodyMore alternative names for the antibody
Dual specificity mitogen activated protein kinase kinase 5 antibody|Dual specificity mitogen-activated protein kinase kinase 5 antibody|EC 126.96.36.199 antibody|HsT17454 antibody|MAP kinase kinase 5 antibody|MAP kinase kinase MEK5b antibody|MAP2K5 antibody|MAPK/ERK kinase 5 antibody|MAPKK 5 antibody|MAPKK5 antibody|MEK 5 antibody|mitogen-activated protein kinase kinase 5 antibody|MKK5 antibody|MP2K5_HUMAN antibody|PRKMK5 antibody|Protein kinase, mitogen-activated, kinase 5 antibody|SAPKK5 antibody|SKK5 antibody
Anti-MEK5 antibody (ab210748)
Anti-MEK5 antibody (ab210748)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Dual specificity mitogen-activated protein kinase kinase 5 protein (1-190AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:5607( Human), Entrez Gene:23938( Mouse), Entrez Gene:29568( Rat), Omim:602520( Human), SwissProt:Q13163( Human), SwissProt:Q9WVS7( Mouse), SwissProt:Q62862( Rat), Unigene:114198( Human), Unigene:325746( Mouse), Unigene:11054( Rat)
|Protein function|| |
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. .
|Protein tissue specificity|| |
Expressed in many adult tissues. Abundant in heart and skeletal muscle.
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. Binds MAP3K2/MAP3K3 and MAPK7 via non-overlapping residues of the PB1 domain. This domain also mediates interactions with SQSTM1 and PARD6A (By similarity).
|Protein post-translational modifications|| |
Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. .; Yersinia yopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway. .
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CUSABIO BIOTECH CO.
|Product type|| |
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