Anti-MARCKSL1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-MARCKSL1 Antibody (CSB-PA013494DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MARCKS-related protein Antibody,MARCKS-like protein 1 Antibody,Macrophage myristoylated alanine-rich C kinase substrate Antibody,Mac-MARCKS Antibody,MacMARCKS Antibody,MARCKSL1 Antibody,MLP Antibody,MRP Antibody

More alternative names for the antibody
F52 antibody|MARCKS-like protein 1 antibody|MARCKSL1 antibody|MLP antibody|MLP1 antibody|MRP antibody|MRP_HUMAN antibody
Anti-MARCKS like protein antibody [EPR15353] – C-terminal (ab184546)
Close sc-130471|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MARCKSL1 Antibody

Catalogue No.

CSB-PA013494DSR2HU

Reactivity

Human

Immunogen

Recombinant human MARCKS-related protein (1-195AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

19 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:65108( Human), Entrez Gene:17357( Mouse), Entrez Gene:100366048( Rat), Entrez Gene:81520( Rat), Omim:602940( Human), SwissProt:P49006( Human), SwissProt:P28667( Mouse), SwissProt:Q9EPH2( Rat), Unigene:707012( Human), Unigene:75061( Human), Unigene:424974( Mouse), Unigene:2486( Rat)

Protein function

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity). .

Protein sequence and domain

Belongs to the MARCKS family.

Protein post-translational modifications

Phosphorylation at Ser-120 and Thr-178 are non-redundantly catalyzed by MAPK8 in vivo. Phosphorylation at Thr-148 is preferentially catalyzed by MAPK8 in vivo, but this modification can also be catalyzed by other kinases in the absence of MAPK8 (By similarity). .

Protein cellular localization

Cytoplasm . Cell membrane . Membrane ; Lipid-anchor . Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity). In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity). .

Research area

All research areas>Signaling Intermediates>MARCKS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!