Anti-MATN3 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MATN3 Antibody (CSB-PA013522ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MATN3 Antibody

More alternative names for the antibody
AV009181 antibody|DIPOA antibody|EDM5 antibody|HOA antibody|MATN3 antibody|MATN3_HUMAN antibody|Matrilin 3 antibody|Matrilin-3 antibody|OADIP antibody|OS2 antibody
Anti-Matrilin 3 antibody (ab106388)
Close sc-98248|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MATN3 Antibody

Catalogue No.

CSB-PA013522ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Matrilin-3 protein (277-486AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

52 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4148( Human), Entrez Gene:17182( Mouse), Entrez Gene:313954( Rat), Omim:602109( Human), SwissProt:O15232( Human), SwissProt:O35701( Mouse), Unigene:656199( Human), Unigene:42226( Mouse)

Protein function

Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.

Protein tissue specificity

Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.

Involvement in disease

Multiple epiphyseal dysplasia 5 (EDM5) [MIM:607078]: A generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. Radiological examination of the skeleton shows delayed, irregular mineralization of the epiphyseal ossification centers and of the centers of the carpal and tarsal bones. Multiple epiphyseal dysplasia is broadly categorized into the more severe Fairbank and the milder Ribbing types. The Fairbank type is characterized by shortness of stature, short and stubby fingers, small epiphyses in several joints, including the knee, ankle, hand, and hip. The Ribbing type is confined predominantly to the hip joints and is characterized by hands that are normal and stature that is normal or near-normal. Multiple epiphyseal dysplasia type 5 is relatively mild and clinically variable. It is primarily characterized by delayed and irregular ossification of the epiphyses and early-onset osteoarthritis. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Spondyloepimetaphyseal dysplasia MATN3-related (SEMD-MATN3) [MIM:608728]: A bone disease characterized by disproportionate early-onset dwarfism, bowing of the lower limbs, lumbar lordosis and normal hands. Skeletal abnormalities include short, wide and stocky long bones with severe epiphyseal and metaphyseal changes, hypoplastic iliac bones and flat, ovoid vertebral bodies. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Osteoarthritis 2 (OS2) [MIM:140600]: A degenerative disease of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis. Clinical symptoms include pain and joint stiffness often leading to significant disability and joint replacement. In the hand, osteoarthritis can develop in the distal interphalangeal and the first carpometacarpal (base of thumb) and proximal interphalangeal joints. Patients with osteoarthritis may have one, a few, or all of these sites affected. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein cellular localization

Secreted.

Research area

All research areas>Structural Proteins>Matrilin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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