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Rabbit Anti-MBTPS1 Antibody (CSB-PA237035ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Membrane-bound transcription factor site-1 protease Antibody,Endopeptidase S1P Antibody,Subtilisin/kexin-isozyme 1 Antibody,SKI-1 Antibody,MBTPS1 Antibody,KIAA0091 Antibody,S1P Antibody,SKI1 AntibodyMore alternative names for the antibody
kexin isozyme 1 antibody|KIAA0091 antibody|MBTPS1 antibody|membrane bound transcription factor peptidase, site 1 antibody|MGC138711 antibody|MGC138712 antibody|PCSK8 antibody|S1P antibody|S1P endopeptidase antibody|Site 1 protease antibody|SKI 1 antibody|SKI1 antibody|Subtilisin isozyme 1 antibody|Subtilisin/kexin isozyme 1 antibody
Anti-S1P antibody (ab140592)
Anti-S1P antibody (ab140592)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Membrane-bound transcription factor site-1 protease protein (803-1052AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. .
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the peptidase S8 family.
|Protein post-translational modifications|| |
The 148 kDa zymogen is processed progressively into two membrane-bound 120 and 106 kDa forms in the endoplasmic reticulum, and late into a secreted 98 kDa form. The propeptide is autocatalytically removed through an intramolecular cleavage after Leu-186. Further cleavage generates 14, 10, and 8 kDa intermediates.
|Protein cellular localization|| |
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Note=May sort to other organelles, including lysosomal and/or endosomal compartments.
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CUSABIO BIOTECH CO.
|Product type|| |
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