Anti-MCF2L Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MCF2L Antibody (CSB-PA521145ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Guanine nucleotide exchange factor DBS Antibody,DBL’s big sister Antibody,MCF2-transforming sequence-like protein Antibody,MCF2L Antibody,KIAA0362 Antibody,OST Antibody

More alternative names for the antibody
ARHGEF 14 antibody|DBL”s big sister antibody|DBS antibody|FLJ12122 antibody|Guanine nucleotide exchange factor DBS antibody|KIAA0362 antibody|MCF 2L antibody|MCF.2 cell line derived transforming sequence like antibody|MCF.2 transforming sequence-like antibody|MCF2 like protein antibody|MCF2 transforming sequence like protein antibody|MCF2-transforming sequence-like protein antibody|Mcf2l antibody|MCF2L_HUMAN antibody|OST antibody|OST oncogene antibody
Anti-ARHGEF14 antibody (ab96395)
Close sc-376400|sc-901|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MCF2L Antibody

Catalogue No.

CSB-PA521145ESR2HU

Reactivity

Human

Immunogen

Recombinant human Guanine nucleotide exchange factor DBS protein (850-980AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

128 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23263( Human), Entrez Gene:17207( Mouse), Entrez Gene:117020( Rat), Omim:609499( Human), SwissProt:O15068( Human), SwissProt:Q64096( Mouse), SwissProt:Q63406( Rat), Unigene:170422( Human), Unigene:334413( Mouse), Unigene:81062( Rat)

Protein function

Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 (PubMed:15157669). .; Isoform 3: Does not catalyze guanine nucleotide exchange on CDC42 (PubMed:15157669). .

Protein sequence and domain

Belongs to the MCF2 family. The CRAL-TRIO domain mediates interaction with various inositol phospholipids, such as phosphatidylinositol 3-phosphate (PI3P), phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 5-phosphate (PI5P).; The DH domain is involved in interaction with CCPG1.

Protein cellular localization

Isoform 5: Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .; Isoform 3: Cytoplasm . Endomembrane system . Note=Interaction with membranes enriched in phosphoinositides is mediated by the CRAL-TRIO domain. .; Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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