Anti-MCM10 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MCM10 Antibody (CSB-PA745335ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Protein MCM10 homolog Antibody,HsMCM10 Antibody,MCM10 Antibody,PRO2249 Antibody

More alternative names for the antibody
FLJ31133 antibody|HsMCM10 antibody|mcm10 antibody|MCM10 minichromosome maintenance deficient 10 antibody|MCM10_HUMAN antibody|Minichromosome maintenance protein 10 isoform 1 antibody|PRO2249 antibody|Protein MCM10 homolog antibody
Anti-MCM10 antibody (ab3733)
Close sc-47111|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MCM10 Antibody

Catalogue No.

CSB-PA745335ESR2HU

Reactivity

Human

Immunogen

Recombinant human Protein MCM10 homolog protein (616-875AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

98 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:55388( Human), Entrez Gene:70024( Mouse), Omim:609357( Human), SwissProt:Q3MIR3( Human), SwissProt:Q5T670( Human), SwissProt:Q7L590( Human), SwissProt:Q9H0D7( Human), SwissProt:Q9H3P9( Human), SwissProt:Q0VBD2( Mouse), SwissProt:Q505F3( Mouse), SwissProt:Q8BMJ1( Mouse), SwissProt:Q8BY66( Mouse), Unigene:198363( Human), Unigene:23828( Mouse), Unigene:447935( Mouse)

Protein function

Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359). .

Protein sequence and domain

Belongs to the MCM10 family. Each zinc finger-like domain binds a zinc ion and is involved in both ssDNA and dsDNA binding, as is the OB-fold domain.; The N-terminal domain mediates homodimerization.

Protein cellular localization

Nucleus . Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase. From early to mid-S phase located in discrete nuclear foci. In early S phase, several hundred foci appeared throughout the nucleus. In mid-S phase, the foci appeared at the nuclear periphery and nucleolar regions. In the late S and G phases localized to nucleoli.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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