Anti-MCMBP Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MCMBP Antibody (CSB-PA880100ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MCM-BP Antibody,MCM-binding protein Antibody,MCMBP Antibody

More alternative names for the antibody
C10orf119 antibody|chromosome 10 open reading frame 119 antibody|MCM-binding protein antibody|MCM-BP antibody|mcmbp antibody|MCMBP_HUMAN antibody|Mini-chromosome maintenance complex-binding protein antibody|Minichromosome maintenance complex binding protein antibody
Anti-MCM-BP antibody (ab122478)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MCMBP Antibody

Catalogue No.

CSB-PA880100ESR2HU

Reactivity

Human

Immunogen

Recombinant human Mini-chromosome maintenance complex-binding protein (1-240AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

72 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79892( Human), Entrez Gene:210711( Mouse), Omim:610909( Human), SwissProt:Q9BTE3 ( Human), SwissProt:Q8R3C0( Mouse), SwissProt:B1H268( Rat), Unigene:124246( Human), Unigene:58882( Mouse)

Protein function

Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. .

Protein sequence and domain

Belongs to the MCMBP family.

Protein cellular localization

Nucleus . Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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