Anti-MEP1B Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MEP1B Antibody (CSB-PA618098ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Meprin A subunit beta Antibody,Endopeptidase-2 Antibody,Meprin B Antibody,N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta Antibody,PABA peptide hydrolase Antibody,PPH beta Antibody,MEP1B Antibody

More alternative names for the antibody
Endopeptidase 2 antibody|Endopeptidase-2 antibody|kinase splitting membranal proteinase antibody|KSMP antibody|Mep1b antibody|MEP1B_HUMAN antibody|Meprin 1 beta subunit antibody|Meprin A beta antibody|Meprin A beta subunit precursor antibody|Meprin A subunit beta antibody|Meprin B antibody|N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit antibody|N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta antibody|PABA peptide hydrolase antibody|PPH beta antibody
Anti-Meprin beta antibody (ab204886)
Close sc-23491|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-MEP1B Antibody

Catalogue No.

CSB-PA618098ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Meprin A subunit beta protein (480-652AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

79 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4225( Human), Omim:600389( Human), SwissProt:Q16820( Human), Unigene:194777( Human)

Protein function

Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1′ position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. .

Protein tissue specificity

The major site of expression is the brush border membrane of small intestinal and kidney epithelial cells. .

Protein sequence and domain

Belongs to the peptidase M12A family.

Protein post-translational modifications

N-glycosylated; contains high mannose and/or complex biantennary structures.; O-glycosylation protect the C-terminal region from proteolytic cleavage and diminish secretion, this seems to be specific to human. .; Proteolytically activated by trypsin in the intestinal lumen and kallikrein-related peptidases in other tissues.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein. Secreted . Note=Homodimers are essentially membrane bound but may also be shed from the surface by ADAM-10 and ADAM-17. .

Research area

All research areas>Signaling Intermediates>Meprin A
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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