Anti-MID1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MID1 Antibody (CSB-PA013819ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

E3 ubiquitin-protein ligase Midline-1 Antibody,Midin Antibody,Putative transcription factor XPRF Antibody,RING finger protein 59 Antibody,RING finger protein Midline-1 Antibody,Tripartite motif-containing protein 18 Antibody,MID1 Antibody,FXY Antibody,RNF59 Antibody,TRIM18 Antibody,XPRF Antibody

More alternative names for the antibody
BBBG 1 antibody|BBBG1 antibody|E3 ubiquitin-protein ligase Midline-1 antibody|Finger on X and Y mouse homolog of antibody|FXY antibody|GBBB 1 antibody|GBBB1 antibody|MID 1 antibody|Mid1 antibody|Midin antibody|Midline 1 (Opitz/BBB syndrome) antibody|Midline 1 antibody|Midline 1 ring finger antibody|Midline 1 RING finger protein antibody|Midline-1 antibody|Midline1 antibody|OGS 1 antibody|OGS1 antibody|OS antibody|OSX antibody|Putative transcription factor XPRF antibody|RING finger protein 59 antibody|RING finger protein Midline-1 antibody|RNF 59 antibody|RNF59 antibody|TRI18 antibody|TRI18_HUMAN antibody|TRIM 18 antibody|TRIM18 antibody|Tripartite motif containing protein 18 antibody|Tripartite motif protein TRIM18 antibody|Tripartite motif-containing protein 18 antibody|XPRF antibody|zinc finger on X and Y, mouse, homolog of antibody|Zinc finger X and Y antibody|ZNFXY antibody
Anti-MID1 antibody (ab70770)
Close sc-293353|sc-55248|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MID1 Antibody

Catalogue No.

CSB-PA013819ESR2HU

Reactivity

Human

Immunogen

Recombinant human E3 ubiquitin-protein ligase Midline-1 protein (478-667AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

75 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4281( Human), Entrez Gene:17318( Mouse), Entrez Gene:54252( Rat), Omim:300552( Human), SwissProt:O15344( Human), SwissProt:O70583( Mouse), SwissProt:P82458( Rat), Unigene:27695( Human), Unigene:689953( Human), Unigene:34441( Mouse), Unigene:444905( Mouse), Unigene:460870( Mouse), Unigene:15169( Rat)

Protein function

Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

Protein tissue specificity

In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.

Involvement in disease

Opitz GBBB syndrome 1 (GBBB1) [MIM:300000]: A congenital midline malformation syndrome characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, cleft lip/palate, laryngotracheoesophageal abnormalities, imperforate anus, developmental delay and congenital heart defects. . Note=The disease is caused by mutations affecting the gene represented in this entry. MID1 mutations produce proteins with a decreased affinity for microtubules.

Protein sequence and domain

Belongs to the TRIM/RBCC family.

Protein post-translational modifications

Phosphorylated on serine and threonine residues. .

Protein cellular localization

Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Note=Microtubule-associated. It is associated with microtubules throughout the cell cycle, co-localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodies during mitosis and cytokinesis.

Research area

All research areas>Transcription Regulators>Ring Finger Protein
(View all antibody categories related to Transcription Regulators)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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