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Rabbit Anti-MID1 Antibody (CSB-PA013819ESR2HU)
Supplier: CUSABIO BIOTECH CO.
E3 ubiquitin-protein ligase Midline-1 Antibody,Midin Antibody,Putative transcription factor XPRF Antibody,RING finger protein 59 Antibody,RING finger protein Midline-1 Antibody,Tripartite motif-containing protein 18 Antibody,MID1 Antibody,FXY Antibody,RNF59 Antibody,TRIM18 Antibody,XPRF AntibodyMore alternative names for the antibody
BBBG 1 antibody|BBBG1 antibody|E3 ubiquitin-protein ligase Midline-1 antibody|Finger on X and Y mouse homolog of antibody|FXY antibody|GBBB 1 antibody|GBBB1 antibody|MID 1 antibody|Mid1 antibody|Midin antibody|Midline 1 (Opitz/BBB syndrome) antibody|Midline 1 antibody|Midline 1 ring finger antibody|Midline 1 RING finger protein antibody|Midline-1 antibody|Midline1 antibody|OGS 1 antibody|OGS1 antibody|OS antibody|OSX antibody|Putative transcription factor XPRF antibody|RING finger protein 59 antibody|RING finger protein Midline-1 antibody|RNF 59 antibody|RNF59 antibody|TRI18 antibody|TRI18_HUMAN antibody|TRIM 18 antibody|TRIM18 antibody|Tripartite motif containing protein 18 antibody|Tripartite motif protein TRIM18 antibody|Tripartite motif-containing protein 18 antibody|XPRF antibody|zinc finger on X and Y, mouse, homolog of antibody|Zinc finger X and Y antibody|ZNFXY antibody
Anti-MID1 antibody (ab70770)
Anti-MID1 antibody (ab70770)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human E3 ubiquitin-protein ligase Midline-1 protein (478-667AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:4281( Human), Entrez Gene:17318( Mouse), Entrez Gene:54252( Rat), Omim:300552( Human), SwissProt:O15344( Human), SwissProt:O70583( Mouse), SwissProt:P82458( Rat), Unigene:27695( Human), Unigene:689953( Human), Unigene:34441( Mouse), Unigene:444905( Mouse), Unigene:460870( Mouse), Unigene:15169( Rat)
|Protein function|| |
Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .
|Protein tissue specificity|| |
In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.
|Involvement in disease|| |
Opitz GBBB syndrome 1 (GBBB1) [MIM:300000]: A congenital midline malformation syndrome characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, cleft lip/palate, laryngotracheoesophageal abnormalities, imperforate anus, developmental delay and congenital heart defects. . Note=The disease is caused by mutations affecting the gene represented in this entry. MID1 mutations produce proteins with a decreased affinity for microtubules.
|Protein sequence and domain|| |
Belongs to the TRIM/RBCC family.
|Protein post-translational modifications|| |
Phosphorylated on serine and threonine residues. .
|Protein cellular localization|| |
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Note=Microtubule-associated. It is associated with microtubules throughout the cell cycle, co-localizing with cytoplasmic fibers in interphase and with the mitotic spindle and midbodies during mitosis and cytokinesis.
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CUSABIO BIOTECH CO.
|Product type|| |
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