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Rabbit Anti-MRC2 Antibody (CSB-PA731055ESR1HU)
Supplier: CUSABIO BIOTECH CO.
C-type mannose receptor 2 Antibody,C-type lectin domain family 13 member E Antibody,Endocytic receptor 180 Antibody,Macrophage mannose receptor 2 Antibody,Urokinase-type plasminogen activator receptor-associated protein Antibody,UPAR-associated protein Antibody,Urokinase receptor-associated protein Antibody,CD280 Antibody,MRC2 Antibody,CLEC13E Antibody,ENDO180 Antibody,KIAA0709 Antibody,UPARAP AntibodyMore alternative names for the antibody
C-type lectin domain family 13 member E antibody|C-type mannose receptor 2 antibody|CD 280 antibody|CD280 antibody|CD280 antigen antibody|CLEC 13E antibody|CLEC13E antibody|ENDO 180 antibody|ENDO180 antibody|Endocytic receptor (macrophage mannose receptor family) antibody|Endocytic receptor 180 antibody|FLJ35911 antibody|KIAA0709 antibody|Macrophage mannose receptor 2 antibody|Mannose receptor C type 2 antibody|MRC 2 antibody|MRC2 antibody|MRC2_HUMAN antibody|UPAR-associated protein antibody|UPARAP antibody|Urokinase plasminogen activator receptor associated protein antibody|Urokinase receptor associated protein antibody|Urokinase receptor-associated protein antibody|Urokinase-type plasminogen activator receptor-associated protein antibody
Anti-MRC2 antibody (ab70132)
Anti-MRC2 antibody (ab70132)
Recommended applications: ELISA, WB
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human C-type mannose receptor 2 protein (120-300AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
|Database links|| |
Entrez Gene:9902( Human), Entrez Gene:17534( Mouse), Entrez Gene:498011( Rat), Omim:612264( Human), SwissProt:Q9UBG0( Human), SwissProt:Q64449( Mouse), SwissProt:Q4TU93( Rat), Unigene:7835( Human), Unigene:235616( Mouse), Unigene:213511( Rat)
|Protein function|| |
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). .
|Protein tissue specificity|| |
Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney. .
|Protein sequence and domain|| |
C-type lectin domains 3 to 8 are not required for calcium-dependent binding of mannose, fucose and N-acetylglucosamine. C-type lectin domain 2 is responsible for sugar-binding in a calcium-dependent manner.; Fibronectin type-II domain mediates collagen-binding.; Ricin B-type lectin domain contacts with the second C-type lectin domain.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
CUSABIO BIOTECH CO.
|Product type|| |
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