Anti-MRC2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MRC2 Antibody (CSB-PA731055ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

C-type mannose receptor 2 Antibody,C-type lectin domain family 13 member E Antibody,Endocytic receptor 180 Antibody,Macrophage mannose receptor 2 Antibody,Urokinase-type plasminogen activator receptor-associated protein Antibody,UPAR-associated protein Antibody,Urokinase receptor-associated protein Antibody,CD280 Antibody,MRC2 Antibody,CLEC13E Antibody,ENDO180 Antibody,KIAA0709 Antibody,UPARAP Antibody

More alternative names for the antibody
C-type lectin domain family 13 member E antibody|C-type mannose receptor 2 antibody|CD 280 antibody|CD280 antibody|CD280 antigen antibody|CLEC 13E antibody|CLEC13E antibody|ENDO 180 antibody|ENDO180 antibody|Endocytic receptor (macrophage mannose receptor family) antibody|Endocytic receptor 180 antibody|FLJ35911 antibody|KIAA0709 antibody|Macrophage mannose receptor 2 antibody|Mannose receptor C type 2 antibody|MRC 2 antibody|MRC2 antibody|MRC2_HUMAN antibody|UPAR-associated protein antibody|UPARAP antibody|Urokinase plasminogen activator receptor associated protein antibody|Urokinase receptor associated protein antibody|Urokinase receptor-associated protein antibody|Urokinase-type plasminogen activator receptor-associated protein antibody
Anti-MRC2 antibody (ab70132)
Close sc-271148|sc-68371|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MRC2 Antibody

Catalogue No.

CSB-PA731055ESR2HU

Reactivity

Human

Immunogen

Recombinant human C-type mannose receptor 2 protein (120-300AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

166 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9902( Human), Entrez Gene:17534( Mouse), Entrez Gene:498011( Rat), Omim:612264( Human), SwissProt:Q9UBG0( Human), SwissProt:Q64449( Mouse), SwissProt:Q4TU93( Rat), Unigene:7835( Human), Unigene:235616( Mouse), Unigene:213511( Rat)

Protein function

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). .

Protein tissue specificity

Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney. .

Protein sequence and domain

C-type lectin domains 3 to 8 are not required for calcium-dependent binding of mannose, fucose and N-acetylglucosamine. C-type lectin domain 2 is responsible for sugar-binding in a calcium-dependent manner.; Fibronectin type-II domain mediates collagen-binding.; Ricin B-type lectin domain contacts with the second C-type lectin domain.

Protein post-translational modifications

N-glycosylated. .

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Lymphocyte Signaling>Endo180
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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