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Rabbit Anti-MUTYH Antibody (CSB-PA883426ESR2HU)
Supplier: CUSABIO BIOTECH CO.
MutY homolog Antibody,hMYH Antibody,MUTYH Antibody,MYH AntibodyMore alternative names for the antibody
A/G specific adenine DNA glycosylase antibody|A/G-specific adenine DNA glycosylase antibody|Adenine DNA glycosylase antibody|CYP2C antibody|hMYH antibody|MGC4416 antibody|MutY (E. coli) homolog antibody|MutY homolog (E. coli) antibody|MutY homolog antibody|MutY, E. coli, homolog of antibody|Mutyh antibody|MUTYH_HUMAN antibody|MYH antibody|rMYH antibody
Anti-MYH antibody (ab55551)
Anti-MYH antibody (ab55551)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human A/G-specific adenine DNA glycosylase protein (1-265AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities. .
|Involvement in disease|| |
Familial adenomatous polyposis 2 (FAP2) [MIM:608456]: A condition characterized by the development of multiple colorectal adenomatous polyps, benign neoplasms derived from glandular epithelium. Some affected individuals may develop colorectal carcinoma. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Gastric cancer (GASC) [MIM:613659]: A malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body. The term gastric cancer or gastric carcinoma refers to adenocarcinoma of the stomach that accounts for most of all gastric malignant tumors. Two main histologic types are recognized, diffuse type and intestinal type carcinomas. Diffuse tumors are poorly differentiated infiltrating lesions, resulting in thickening of the stomach. In contrast, intestinal tumors are usually exophytic, often ulcerating, and associated with intestinal metaplasia of the stomach, most often observed in sporadic disease. . Note=The gene represented in this entry may be involved in disease pathogenesis. Somatic mutations contribute to the development of a sub-set of sporadic gastric cancers in carriers of Helicobacter pylori (PubMed:15273732). .
|Protein sequence and domain|| |
Belongs to the Nth/MutY family.
|Protein cellular localization|| |
Nucleus . Mitochondrion .
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CUSABIO BIOTECH CO.
|Product type|| |
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