Anti-MUTYH Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-MUTYH Antibody (CSB-PA883426ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MutY homolog Antibody,hMYH Antibody,MUTYH Antibody,MYH Antibody

More alternative names for the antibody
A/G specific adenine DNA glycosylase antibody|A/G-specific adenine DNA glycosylase antibody|Adenine DNA glycosylase antibody|CYP2C antibody|hMYH antibody|MGC4416 antibody|MutY (E. coli) homolog antibody|MutY homolog (E. coli) antibody|MutY homolog antibody|MutY, E. coli, homolog of antibody|Mutyh antibody|MUTYH_HUMAN antibody|MYH antibody|rMYH antibody
Anti-MYH antibody (ab55551)
Close sc-374571|sc-30633|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-MUTYH Antibody

Catalogue No.

CSB-PA883426ESR2HU

Reactivity

Human

Immunogen

Recombinant human A/G-specific adenine DNA glycosylase protein (1-265AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

60 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4595( Human), SwissProt:Q9UIF7( Human), Unigene:271353( Human)

Protein function

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities. .

Involvement in disease

Familial adenomatous polyposis 2 (FAP2) [MIM:608456]: A condition characterized by the development of multiple colorectal adenomatous polyps, benign neoplasms derived from glandular epithelium. Some affected individuals may develop colorectal carcinoma. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Gastric cancer (GASC) [MIM:613659]: A malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body. The term gastric cancer or gastric carcinoma refers to adenocarcinoma of the stomach that accounts for most of all gastric malignant tumors. Two main histologic types are recognized, diffuse type and intestinal type carcinomas. Diffuse tumors are poorly differentiated infiltrating lesions, resulting in thickening of the stomach. In contrast, intestinal tumors are usually exophytic, often ulcerating, and associated with intestinal metaplasia of the stomach, most often observed in sporadic disease. . Note=The gene represented in this entry may be involved in disease pathogenesis. Somatic mutations contribute to the development of a sub-set of sporadic gastric cancers in carriers of Helicobacter pylori (PubMed:15273732). .

Protein sequence and domain

Belongs to the Nth/MutY family.

Protein cellular localization

Nucleus . Mitochondrion .

Research area

All research areas>Tumor Suppressor/Apoptosis>MUTYH
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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