Anti-NAMPT Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NAMPT Antibody (CSB-PA015422ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

NAmPRTase Antibody,Nampt Antibody,Pre-B-cell colony-enhancing factor 1 Antibody,Pre-B cell-enhancing factor Antibody,NAMPT Antibody,PBEF Antibody,PBEF1 Antibody

More alternative names for the antibody
1110035O14Rik antibody|AI314458 antibody|AI480535 antibody|DKFZP666B131 antibody|EC 2.4.2.12 antibody|MGC117256 antibody|NAmPRTase antibody|Nampt antibody|NAMPT_HUMAN antibody|Nicotinamide phosphoribosyltransferase antibody|PBEF 1 antibody|PBEF antibody|PBEF1 antibody|Pre B cell colony enhancing factor 1 antibody|Pre B cell colony enhancing factor antibody|Pre B cell enhancing factor antibody|Pre-B cell-enhancing factor antibody|Pre-B-cell colony-enhancing factor 1 antibody|VF antibody|Visfatin antibody
Anti-Visfatin antibody (ab45890)
Close sc-130058|sc-46440|sc-166866|sc-393444|sc-393443|sc-393510|sc-166946|sc-67020|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-NAMPT Antibody

Catalogue No.

CSB-PA015422ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Nicotinamide phosphoribosyltransferase protein (1-280AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

55 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10135( Human), Entrez Gene:59027( Mouse), Entrez Gene:297508( Rat), Omim:608764( Human), SwissProt:P43490( Human), SwissProt:Q99KQ4( Mouse), SwissProt:Q80Z29( Rat), Unigene:489615( Human), Unigene:202727( Mouse), Unigene:203508( Rat)

Protein function

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity). .

Protein tissue specificity

Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.

Protein sequence and domain

Belongs to the NAPRTase family.

Protein cellular localization

Nucleus . Cytoplasm . Secreted . Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. .

Research area

All research areas>Lymphocyte Signaling>PBEF
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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