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Rabbit Anti-NAMPT Antibody (CSB-PA015422ESR1HU)
Supplier: CUSABIO BIOTECH CO.
NAmPRTase Antibody,Nampt Antibody,Pre-B-cell colony-enhancing factor 1 Antibody,Pre-B cell-enhancing factor Antibody,NAMPT Antibody,PBEF Antibody,PBEF1 AntibodyMore alternative names for the antibody
1110035O14Rik antibody|AI314458 antibody|AI480535 antibody|DKFZP666B131 antibody|EC 18.104.22.168 antibody|MGC117256 antibody|NAmPRTase antibody|Nampt antibody|NAMPT_HUMAN antibody|Nicotinamide phosphoribosyltransferase antibody|PBEF 1 antibody|PBEF antibody|PBEF1 antibody|Pre B cell colony enhancing factor 1 antibody|Pre B cell colony enhancing factor antibody|Pre B cell enhancing factor antibody|Pre-B cell-enhancing factor antibody|Pre-B-cell colony-enhancing factor 1 antibody|VF antibody|Visfatin antibody
Anti-Visfatin antibody (ab45890)
Anti-Visfatin antibody (ab45890)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Nicotinamide phosphoribosyltransferase protein (1-280AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:10135( Human), Entrez Gene:59027( Mouse), Entrez Gene:297508( Rat), Omim:608764( Human), SwissProt:P43490( Human), SwissProt:Q99KQ4( Mouse), SwissProt:Q80Z29( Rat), Unigene:489615( Human), Unigene:202727( Mouse), Unigene:203508( Rat)
|Protein function|| |
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity). .
|Protein tissue specificity|| |
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
|Protein sequence and domain|| |
Belongs to the NAPRTase family.
|Protein cellular localization|| |
Nucleus . Cytoplasm . Secreted . Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. .
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CUSABIO BIOTECH CO.
|Product type|| |
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