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Rabbit Anti-NCAPH Antibody (CSB-PA621857DSR1HU)
Supplier: CUSABIO BIOTECH CO.
Barren homolog protein 1 Antibody,Chromosome-associated protein H Antibody,Non-SMC condensin I complex subunit H Antibody,XCAP-H homolog Antibody,NCAPH Antibody,BRRN Antibody, BRRN1 Antibody, CAPH AntibodyMore alternative names for the antibody
Barren Drosophila Homolog of 1 antibody|Barren homolog protein 1 antibody|BRRN antibody|BRRN1 antibody|CAP H antibody|CAPH antibody|Chromosome associated protein H antibody|Chromosome-associated protein H antibody|CND2_HUMAN antibody|Condensin complex subunit 2 antibody|Condensin subunit 2 antibody|Condensin-2 complex subunit H2 antibody|Condesin antibody|HCAP H antibody|hCAP-H antibody|KIAA0074 antibody|mCAP H antibody|MGC4616 antibody|Ncaph antibody|Non SMC condensin I complex subunit H antibody|Non-SMC condensin I complex subunit H antibody|XCAP H homolog antibody|XCAP-H homolog antibody
Anti-BRRN1 antibody (ab154105)
Anti-BRRN1 antibody (ab154105)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Condensin complex subunit 2 protein (1-250AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. .
|Protein tissue specificity|| |
Widely expressed at low level. Expressed in proliferating cells. .
|Protein sequence and domain|| |
Belongs to the CND2 (condensin subunit 2) family.
|Protein post-translational modifications|| |
Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity). .
|Protein cellular localization|| |
Nucleus . Cytoplasm . Chromosome . Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin’s association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
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CUSABIO BIOTECH CO.
|Product type|| |
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