Anti-NCAPH Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NCAPH Antibody (CSB-PA621857DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Barren homolog protein 1 Antibody,Chromosome-associated protein H Antibody,Non-SMC condensin I complex subunit H Antibody,XCAP-H homolog Antibody,NCAPH Antibody,BRRN Antibody, BRRN1 Antibody, CAPH Antibody

More alternative names for the antibody
Barren Drosophila Homolog of 1 antibody|Barren homolog protein 1 antibody|BRRN antibody|BRRN1 antibody|CAP H antibody|CAPH antibody|Chromosome associated protein H antibody|Chromosome-associated protein H antibody|CND2_HUMAN antibody|Condensin complex subunit 2 antibody|Condensin subunit 2 antibody|Condensin-2 complex subunit H2 antibody|Condesin antibody|HCAP H antibody|hCAP-H antibody|KIAA0074 antibody|mCAP H antibody|MGC4616 antibody|Ncaph antibody|Non SMC condensin I complex subunit H antibody|Non-SMC condensin I complex subunit H antibody|XCAP H homolog antibody|XCAP-H homolog antibody
Anti-BRRN1 antibody (ab154105)
Close sc-101013|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-NCAPH Antibody

Catalogue No.

CSB-PA621857DSR1HU

Reactivity

Human

Immunogen

Recombinant human Condensin complex subunit 2 protein (1-250AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

82 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23397( Human), Entrez Gene:215387( Mouse), Omim:602332( Human), SwissProt:Q15003( Human), SwissProt:Q8C156( Mouse), Unigene:308045( Human), Unigene:29786( Mouse)

Protein function

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. .

Protein tissue specificity

Widely expressed at low level. Expressed in proliferating cells. .

Protein sequence and domain

Belongs to the CND2 (condensin subunit 2) family.

Protein post-translational modifications

Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity). .

Protein cellular localization

Nucleus . Cytoplasm . Chromosome . Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin’s association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.

Research area

All research areas>Transcription Regulators>hCAP
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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