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Rabbit Anti-NECTIN3 Antibody (CSB-PA882076ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Nectin-3 Antibody,CDw113 Antibody,Nectin cell adhesion molecule 3 Antibody,NECTIN3 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Nectin-3 protein (310-549AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body. .
|Protein tissue specificity|| |
Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines. .
|Protein sequence and domain|| |
Belongs to the nectin family.
|Protein cellular localization|| |
Cell membrane ; Single-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane .
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CUSABIO BIOTECH CO.
|Product type|| |
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