Anti-NME1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NME1 Antibody (CSB-PA02775A0Rb)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

NDK A Antibody,NDP kinase A Antibody,A-activated DNase Antibody,GAAD Antibody,Metastasis inhibition factor nm23 Antibody,Tumor metastatic process-associated protein Antibody,nm23-H1 Antibody

More alternative names for the antibody
AWD antibody|AWD, drosophila, homolog of antibody|GAAD antibody|Granzyme A activated DNase antibody|Granzyme A-activated DNase antibody|GZMA activated DNase antibody|Metastasis inhibition factor NM23 antibody|NB antibody|NBS antibody|NDK A antibody|NDKA antibody|NDKA_HUMAN antibody|NDP kinase A antibody|NDPK-A antibody|NDPKA antibody|NM23 antibody|NM23 long variant, included antibody|nm23-H1 antibody|NM23-M1 antibody|NM23H1B, included antibody|NME/NM23 nucleoside diphosphate kinase 1 antibody|Nme1 antibody|NME1-NME2 spliced read-through transcript, included antibody|Non-metastatic cells 1, protein (NM23A) expressed in antibody|Nonmetastatic cells 1, protein expressed in antibody|Nonmetastatic protein 23 antibody|Nonmetastatic protein 23, homolog 1 antibody|Nucleoside diphosphate kinase A antibody|Tumor metastatic process-associated protein antibody
Anti-NM23A antibody (ab154547)
Close sc-343|sc-514515|sc-14787|sc-17586|sc-465|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-NME1 Antibody

Catalogue No.

CSB-PA02775A0Rb

Reactivity

Human

Immunogen

Recombinant human Nucleoside diphosphate kinase A protein (2-152AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

17 kDa

Purification

Caprylic Acid Ammonium Sulfate Precipitation purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4830( Human), Entrez Gene:18102( Mouse), Entrez Gene:191575( Rat), Omim:156490( Human), SwissProt:P15531( Human), SwissProt:P15532( Mouse), SwissProt:Q05982( Rat), Unigene:463456( Human), Unigene:439702( Mouse), Unigene:6236( Rat)

Protein function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3′-5′ exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3′ end to enhance DNA damage and prevent DNA end reannealing and rapid repair. .

Protein tissue specificity

Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. .

Protein sequence and domain

Belongs to the NDK family.

Protein cellular localization

Cytoplasm . Nucleus . Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.

Research area

All research areas>Kinases and Phosphatases>nm23-H
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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