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Rabbit Anti-NME1 Antibody (CSB-PA02775A0Rb)
Supplier: CUSABIO BIOTECH CO.
NDK A Antibody,NDP kinase A Antibody,A-activated DNase Antibody,GAAD Antibody,Metastasis inhibition factor nm23 Antibody,Tumor metastatic process-associated protein Antibody,nm23-H1 AntibodyMore alternative names for the antibody
AWD antibody|AWD, drosophila, homolog of antibody|GAAD antibody|Granzyme A activated DNase antibody|Granzyme A-activated DNase antibody|GZMA activated DNase antibody|Metastasis inhibition factor NM23 antibody|NB antibody|NBS antibody|NDK A antibody|NDKA antibody|NDKA_HUMAN antibody|NDP kinase A antibody|NDPK-A antibody|NDPKA antibody|NM23 antibody|NM23 long variant, included antibody|nm23-H1 antibody|NM23-M1 antibody|NM23H1B, included antibody|NME/NM23 nucleoside diphosphate kinase 1 antibody|Nme1 antibody|NME1-NME2 spliced read-through transcript, included antibody|Non-metastatic cells 1, protein (NM23A) expressed in antibody|Nonmetastatic cells 1, protein expressed in antibody|Nonmetastatic protein 23 antibody|Nonmetastatic protein 23, homolog 1 antibody|Nucleoside diphosphate kinase A antibody|Tumor metastatic process-associated protein antibody
Anti-NM23A antibody (ab154547)
Anti-NM23A antibody (ab154547)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Nucleoside diphosphate kinase A protein (2-152AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Caprylic Acid Ammonium Sulfate Precipitation purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:4830( Human), Entrez Gene:18102( Mouse), Entrez Gene:191575( Rat), Omim:156490( Human), SwissProt:P15531( Human), SwissProt:P15532( Mouse), SwissProt:Q05982( Rat), Unigene:463456( Human), Unigene:439702( Mouse), Unigene:6236( Rat)
|Protein function|| |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3′-5′ exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3′ end to enhance DNA damage and prevent DNA end reannealing and rapid repair. .
|Protein tissue specificity|| |
Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. .
|Protein sequence and domain|| |
Belongs to the NDK family.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
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CUSABIO BIOTECH CO.
|Product type|| |
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