Anti-NR2C2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-NR2C2 Antibody (CSB-PA016052ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Orphan nuclear receptor TAK1 Antibody,Orphan nuclear receptor TR4 Antibody,Testicular receptor 4 Antibody,NR2C2 Antibody,TAK1 Antibody,TR4 Antibody

More alternative names for the antibody
hTAK1 antibody|Nr2c2 antibody|NR2C2_HUMAN antibody|Nuclear hormone receptor TR4 antibody|Nuclear receptor subfamily 2 group C member 2 antibody|Orphan nuclear receptor TAK1 antibody|Orphan nuclear receptor TR4 antibody|TAK1 antibody|Testicular nuclear receptor 4 antibody|Testicular receptor 4 antibody|TR2R1 antibody|TR4 antibody|TR4 nuclear hormone receptor antibody
Anti-NR2C2 antibody (ab137582)
Close

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-NR2C2 Antibody

Catalogue No.

CSB-PA016052ESR1HU

Reactivity

Human

Immunogen

Recombinant human Nuclear receptor subfamily 2 group C member 2 protein (240-380AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

65 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7182( Human), Entrez Gene:22026( Mouse), Entrez Gene:50659( Rat), Omim:601426( Human), SwissProt:P49116( Human), SwissProt:P49117( Mouse), SwissProt:P55094( Rat), Unigene:555973( Human), Unigene:442385( Mouse), Unigene:476867( Mouse), Unigene:87062( Mouse), Unigene:10485( Rat)

Protein function

Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5′-AGGTCA-3′ half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation. .

Protein sequence and domain

Belongs to the nuclear hormone receptor family. NR2 subfamily.

Protein post-translational modifications

Phosphorylation on Ser-19 and Ser-68 is an important regulator of NR2C2-mediated transcriptional activity. Phosphorylation on these residues recruits the corepressor, NRIP1, leading to transcripional repression, whereas the non-phosphorylated form preferentially recruits the coactivator, PCAF (By similarity). .

Protein cellular localization

Nucleus .

Research area

All research areas>Steroid Receptors>Testicular Orphan Receptor
(View all antibody categories related to Steroid Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!