Anti-NRXN1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NRXN1 Antibody (CSB-PA347832ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Neurexin-1 Antibody,Neurexin I-alpha Antibody,Neurexin-1-alpha Antibody,NRXN1 Antibody,KIAA0578 Antibody

More alternative names for the antibody
DKFZp313P2036 antibody|FLJ35941 antibody|Hs.22998 antibody|KIAA0578 antibody|Neurexin 1 alpha antibody|Neurexin 1 beta antibody|Neurexin I-alpha antibody|Neurexin-1 antibody|Neurexin-1-alpha antibody|NRX1A_HUMAN antibody|NRXN1 antibody|PTHSL2 antibody|SCZD17 antibody
Anti-Neurexin 1 antibody (ab77596)
Close sc-14334|sc-136001|sc-14332|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-NRXN1 Antibody

Catalogue No.

CSB-PA347832ESR2HU

Reactivity

Human

Immunogen

Recombinant human Neurexin-1 protein (31-310AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

161 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9378( Human), Entrez Gene:18189( Mouse), Entrez Gene:60391( Rat), Omim:600565( Human), SwissProt:Q9ULB1( Human), SwissProt:Q9CS84( Mouse), SwissProt:Q63372( Rat), Unigene:637685( Human), Unigene:478418( Mouse), Unigene:491332( Mouse), Unigene:54924( Rat)

Protein function

Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity). .

Protein tissue specificity

Brain. .

Protein sequence and domain

Belongs to the neurexin family.

Protein post-translational modifications

N-glycosylated. .; O-glycosylated. .

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Note=Localized on the pre-synaptic membrane. .

Research area

All research areas>Neurobiology Antibodies>Neurexin
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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