No products in the cart.
Rabbit Anti-NRXN1 Antibody (CSB-PA347832ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Neurexin-1 Antibody,Neurexin I-alpha Antibody,Neurexin-1-alpha Antibody,NRXN1 Antibody,KIAA0578 AntibodyMore alternative names for the antibody
DKFZp313P2036 antibody|FLJ35941 antibody|Hs.22998 antibody|KIAA0578 antibody|Neurexin 1 alpha antibody|Neurexin 1 beta antibody|Neurexin I-alpha antibody|Neurexin-1 antibody|Neurexin-1-alpha antibody|NRX1A_HUMAN antibody|NRXN1 antibody|PTHSL2 antibody|SCZD17 antibody
Anti-Neurexin 1 antibody (ab77596)
Anti-Neurexin 1 antibody (ab77596)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Neurexin-1 protein (31-310AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:9378( Human), Entrez Gene:18189( Mouse), Entrez Gene:60391( Rat), Omim:600565( Human), SwissProt:Q9ULB1( Human), SwissProt:Q9CS84( Mouse), SwissProt:Q63372( Rat), Unigene:637685( Human), Unigene:478418( Mouse), Unigene:491332( Mouse), Unigene:54924( Rat)
|Protein function|| |
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity). .
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the neurexin family.
|Protein post-translational modifications|| |
N-glycosylated. .; O-glycosylated. .
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . Note=Localized on the pre-synaptic membrane. .
AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.
CUSABIO BIOTECH CO.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: