Anti-NTRK3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NTRK3 Antibody (CSB-PA621947ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

GP145-TrkC Antibody,Trk-C Antibody,Neurotrophic tyrosine kinase receptor type 3 Antibody,TrkC tyrosine kinase Antibody,NTRK3 Antibody,TRKC Antibody

More alternative names for the antibody
EC 2.7.10.1 antibody|ETV6 NTRK3 fusion antibody|GP145 TrkC antibody|gp145(trkC) antibody|GP145-TrkC antibody|GP145TrkC antibody|Neurotrophic tyrosine kinase receptor type 3 antibody|Neurotrophin 3 receptor antibody|NT 3 growth factor receptor antibody|NT 3 growth factor receptor precursor antibody|NT 3 receptor antibody|NT-3 growth factor receptor antibody|Ntrk3 antibody|NTRK3_HUMAN antibody|OTTHUMP00000192915 antibody|TRK C antibody|Trk-C antibody|TRKC antibody|TrkC tyrosine kinase antibody|Tyrosine kinase receptor C antibody
Anti-VEGF Receptor 1 antibody [Y103] (ab32152)
Close sc-316|sc-271789|sc-9029|sc-31173|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-NTRK3 Antibody

Catalogue No.

CSB-PA621947ESR1HU

Reactivity

Human

Immunogen

Recombinant human NT-3 growth factor receptor protein (40-300AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

94 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2321( Human), Entrez Gene:14254( Mouse), Entrez Gene:54251( Rat), Omim:165070( Human), SwissProt:P17948( Human), SwissProt:P35969( Mouse), SwissProt:P53767( Rat), Unigene:594454( Human), Unigene:389712( Mouse), Unigene:10239( Rat)

Protein function

Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. .

Protein tissue specificity

Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.

Involvement in disease

Note=Defects in NTRK3 are associated with susceptibility to congenital heart defects (CHD). A disease characterized by congenital developmental abnormalities involving structures of the heart. CHD are the most common major birth defects and the leading cause of death from congenital malformations. .

Protein sequence and domain

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

Protein post-translational modifications

Ligand-mediated auto-phosphorylation.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Neurobiology Antibodies>Trk
(View all antibody categories related to Neurobiology Antibodies)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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