Anti-NUMB Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-NUMB Antibody (CSB-PA016186DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Protein numb homolog Antibody,h-Numb Antibody,Protein S171 Antibody,NUMB Antibody

More alternative names for the antibody
c14_5527 antibody|C14orf41 antibody|FLJ31314 antibody|h Numb antibody|h-Numb antibody|Numb antibody|Numb homolog (Drosophila) antibody|Numb homolog antibody|Numb protein homolog antibody|NUMB_HUMAN antibody|Protein numb homolog antibody|Protein S171 antibody|S171 antibody
Anti-NUMB antibody (ab14140)
Close sc-136554|sc-25668|sc-15590|

Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-NUMB Antibody

Catalogue No.

CSB-PA016186DSR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Protein numb homolog protein (532-651AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

70 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8650( Human), Entrez Gene:18222( Mouse), Entrez Gene:29419( Rat), Entrez Gene:692064( Zebrafish), Omim:603728( Human), SwissProt:P49757( Human), SwissProt:Q9QZS3( Mouse), SwissProt:Q2LC84( Rat), Unigene:654609( Human), Unigene:714879( Human), Unigene:4390( Mouse), Unigene:102078( Rat)

Protein function

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Protein post-translational modifications

Phosphorylated on Ser-276 and Ser-295 by CaMK1. .; Isoform 1 and isoform 2 are ubiquitinated by LNX leading to their subsequent proteasomal degradation (By similarity). Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. .

Protein cellular localization

Membrane; Peripheral membrane protein.

Research area

All research areas>Neurobiology Antibodies>NUMB
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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