Anti-OPHN1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-OPHN1 Antibody (CSB-PA016348ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Oligophrenin-1 Antibody,OPHN1 Antibody

More alternative names for the antibody
ARHGAP41 antibody|Mental retardation, X linked 60 antibody|MRX60 antibody|Oligophrenin 1 antibody|Oligophrenin 1, Rho GTPase activating protein antibody|OPN1 antibody
Anti-OPHN1 antibody (ab210949)
Close sc-374330|sc-8374|sc-376640|sc-376319|sc-376462|sc-376037|sc-376038|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-OPHN1 Antibody

Catalogue No.

CSB-PA016348ESR2HU

Reactivity

Human

Immunogen

Recombinant human Oligophrenin-1 protein (1-270AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

91 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:4983( Human), Omim:300127( Human), SwissProt:O60890( Human)

Protein function

Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity). .

Protein tissue specificity

Expressed in brain.

Involvement in disease

Mental retardation, X-linked, syndromic, OPHN1-related (MRXSO) [MIM:300486]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXSO patients manifest mental retardation associated with cerebellar hypoplasia and distinctive facial dysmorphism. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein cellular localization

Cell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite . Cytoplasm . Note=Present in both presynaptic and postsynaptic sites. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!