Anti-PACSIN2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PACSIN2 Antibody (CSB-PA890765ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Protein kinase C and casein kinase substrate in neurons protein 2 Antibody,Syndapin-2 Antibody,Syndapin-II Antibody,PACSIN2 Antibody

More alternative names for the antibody
cytoplasmic phosphoprotein PACSIN2 antibody|OTTHUMP00000198281 antibody|OTTHUMP00000198282 antibody|OTTHUMP00000198283 antibody|OTTHUMP00000198284 antibody|PACN2_HUMAN antibody|Pacsin2 antibody|protein kinase C and casein kinase substrate in neurons 2 antibody|Protein kinase C and casein kinase substrate in neurons protein 2 antibody|SDPII antibody|Syndapin II antibody
Anti-PACSIN2 antibody (ab37615)
Close sc-390136|sc-10417|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-PACSIN2 Antibody

Catalogue No.

CSB-PA890765ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Protein kinase C and casein kinase substrate in neurons protein 2 protein (240-410AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

55 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:11252( Human), Entrez Gene:23970( Mouse), Omim:604960( Human), SwissProt:Q9UNF0( Human), SwissProt:Q9WVE8( Mouse), Unigene:162877( Human), Unigene:23978( Mouse)

Protein function

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis. .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

Belongs to the PACSIN family. The F-BAR domain forms a coiled coil and mediates membrane-binding and membrane tubulation. In the autoinhibited conformation, interaction with the SH3 domain inhibits membrane tubulation mediated by the F-BAR domain.

Protein post-translational modifications

Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). .

Protein cellular localization

Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection . Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1.

Research area

All research areas>Neurobiology Antibodies>PACSIN
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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