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Rabbit Anti-PACSIN2 Antibody (CSB-PA890765ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Protein kinase C and casein kinase substrate in neurons protein 2 Antibody,Syndapin-2 Antibody,Syndapin-II Antibody,PACSIN2 AntibodyMore alternative names for the antibody
cytoplasmic phosphoprotein PACSIN2 antibody|OTTHUMP00000198281 antibody|OTTHUMP00000198282 antibody|OTTHUMP00000198283 antibody|OTTHUMP00000198284 antibody|PACN2_HUMAN antibody|Pacsin2 antibody|protein kinase C and casein kinase substrate in neurons 2 antibody|Protein kinase C and casein kinase substrate in neurons protein 2 antibody|SDPII antibody|Syndapin II antibody
Anti-PACSIN2 antibody (ab37615)
Anti-PACSIN2 antibody (ab37615)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Protein kinase C and casein kinase substrate in neurons protein 2 protein (240-410AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis. .
|Protein tissue specificity|| |
Widely expressed. .
|Protein sequence and domain|| |
Belongs to the PACSIN family. The F-BAR domain forms a coiled coil and mediates membrane-binding and membrane tubulation. In the autoinhibited conformation, interaction with the SH3 domain inhibits membrane tubulation mediated by the F-BAR domain.
|Protein post-translational modifications|| |
Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). .
|Protein cellular localization|| |
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Recycling endosome membrane. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection . Membrane, caveola. Note=Detected at the neck of flask-shaped caveolae. Localization to tubular recycling endosomes probably requires interaction with MICALL1 and EHD1.
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CUSABIO BIOTECH CO.
|Product type|| |
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