Anti-PAK6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PAK6 Antibody (CSB-PA865108ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

PAK-5 Antibody,p21-activated kinase 6 Antibody,PAK-6 Antibody,PAK6 Antibody,PAK5 Antibody

More alternative names for the antibody
CDKN1A activated kinase 6 antibody|EC 2.7.1.37 antibody|p21 activated protein kinase 6 antibody|p21 protein (Cdc42/Rac)-activated kinase 6 antibody|p21(CDKN1A) activated kinase 6 antibody|p21-activated kinase 6 antibody|p21activated kinase 6 antibody|PAK 5 antibody|PAK 6 antibody|PAK-5 antibody|PAK-6 antibody|PAK5 antibody|Pak6 antibody|PAK6_HUMAN antibody|Serine threonine protein kinase PAK 6 antibody|Serine/threonine protein kinase PAK 6 antibody|Serine/threonine protein kinase PAK6 antibody|Serine/threonine-protein kinase PAK 6 antibody
Anti-PAK6 antibody (ab37749)
Close sc-393102|sc-32857|sc-393075|sc-25975|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PAK6 Antibody

Catalogue No.

CSB-PA865108ESR2HU

Reactivity

Human

Immunogen

Recombinant human Serine/threonine-protein kinase PAK 6 protein (1-270AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

74 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:539224( Cow), Entrez Gene:56924( Human), Entrez Gene:296078( Rat), Omim:608110( Human), SwissProt:Q9NQU5( Human), Unigene:513645( Human)

Protein function

Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD. .

Protein tissue specificity

Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast. .

Protein sequence and domain

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Protein post-translational modifications

Autophosphorylated. Phosphorylated by MAP2K6//MAPKK6, leading to PAK6 activation. .

Protein cellular localization

Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.

Research area

All research areas>Kinases and Phosphatases>PAK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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