Anti-PDGFD Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PDGFD Antibody (CSB-PA887935ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

PDGF-D Antibody,Iris-expressed growth factor Antibody,Spinal cord-derived growth factor B Antibody,SCDGF-B Antibody,PDGFD latent form Antibody,PDGFD receptor-binding form Antibody,PDGFD Antibody,IEGF Antibody,SCDGFB Antibody

More alternative names for the antibody
IEGF antibody|Iris expressed growth factor antibody|Iris-expressed growth factor antibody|MGC26867 antibody|MSTP036 antibody|PDGF D antibody|PDGF-D antibody|PDGFD antibody|PDGFD latent form antibody|PDGFD receptor-binding form antibody|PDGFD_HUMAN antibody|Platelet derived growth factor D antibody|Platelet-derived growth factor D antibody|receptor-binding form antibody|rSCDGF-B antibody|SCDGF B antibody|SCDGF-B antibody|Spinal cord derived growth factor B antibody|Spinal cord-derived growth factor B antibody|spinal-cord derived growth factor-B protein antibody
Anti-SCDGFB antibody [EPR7266(2)] (ab181845)
Close sc-137030|sc-137031|sc-137029|sc-23573|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PDGFD Antibody

Catalogue No.

CSB-PA887935ESR2HU

Reactivity

Human

Immunogen

Recombinant human Platelet-derived growth factor D protein (191-370AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

42 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:80310( Human), Entrez Gene:71785( Mouse), Entrez Gene:66018( Rat), Omim:609673( Human), SwissProt:Q9GZP0( Human), SwissProt:Q925I7( Mouse), SwissProt:Q9EQT1( Rat), Unigene:352298( Human), Unigene:390122( Mouse), Unigene:64493( Rat)

Protein function

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity). .

Protein tissue specificity

Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate, testis, small intestine, spleen and colon. In the kidney, expressed by the visceral epithelial cells of the glomeruli. A widespread expression is also seen in the medial smooth muscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae in the medullary area. Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines. .

Protein sequence and domain

Belongs to the PDGF/VEGF growth factor family.

Protein post-translational modifications

Activated by proteolytic cleavage. Proteolytic removal of the N-terminal CUB domain releasing the core domain is necessary for unmasking the receptor-binding epitopes of the core domain. Cleavage after Arg-247 or Arg-249 by urokinase plasminogen activator gives rise to the active form.

Protein cellular localization

Secreted . Note=Released by platelets upon wounding.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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