Anti-PDK3 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-PDK3 Antibody (CSB-PA613585ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3 Antibody,mitochondrial Antibody,Pyruvate dehydrogenase kinase isoform 3 Antibody,PDK3 Antibody,PDHK3 Antibody

More alternative names for the antibody
[Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody|[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody|CMTX6 antibody|GS1-358P8.4 antibody|mitochondrial antibody|PDK3 antibody|PDK3_HUMAN antibody|Pyruvate dehydrogenase kinase isoenzyme 3 antibody|Pyruvate dehydrogenase kinase isoform 3 antibody|Pyruvate dehydrogenase kinase isozyme 3 antibody|Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody
Anti-PDK3 antibody (ab154549)
Close sc-14490|sc-365378|sc-14488|sc-100535|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-PDK3 Antibody

Catalogue No.

CSB-PA613585ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

46 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5165( Human), Entrez Gene:236900( Mouse), Entrez Gene:296849( Rat), Omim:602526( Human), SwissProt:Q15120( Human), SwissProt:Q922H2( Mouse), Unigene:296031( Human), Unigene:12775( Mouse), Unigene:18101( Rat)

Protein function

Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species. .

Protein tissue specificity

Expressed in heart, skeletal muscle, spinal cord, as well as fetal and adult brain. .

Involvement in disease

Charcot-Marie-Tooth disease, X-linked dominant, 6 (CMTX6) [MIM:300905]: A form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies characterized by severely reduced motor nerve conduction velocities (NCVs) (less than 38m/s) and segmental demyelination and remyelination, and primary peripheral axonal neuropathies characterized by normal or mildly reduced NCVs and chronic axonal degeneration and regeneration on nerve biopsy. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the PDK/BCKDK protein kinase family.

Protein cellular localization

Mitochondrion matrix.

Research area

All research areas>Synthesis and Degradation>PDK
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!