Anti-PEX19 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PEX19 Antibody (CSB-PA017802DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Peroxisomal biogenesis factor 19 Antibody,33 kDa housekeeping protein Antibody,Peroxin-19 Antibody,Peroxisomal farnesylated protein Antibody,PEX19 Antibody,HK33 Antibody,PXF Antibody,OK/SW-cl.22 Antibody

More alternative names for the antibody
33 kDa housekeeping protein antibody|D1S2223E antibody|HK33 antibody|Housekeeping gene 33kD antibody|OK/SW-cl.22 antibody|PBD12A antibody|Peroxin 19 antibody|Peroxin-19 antibody|Peroxisomal biogenesis factor 19 antibody|Peroxisomal farnesylated protein antibody|PEX19 antibody|PEX19_HUMAN antibody|PMP1 antibody|PMPI antibody|PXF antibody|PXMP1 antibody
Anti-PEX19 antibody [EPR9266(B)] (ab137072)
Close sc-136029|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PEX19 Antibody

Catalogue No.

CSB-PA017802DSR2HU

Reactivity

Human

Immunogen

Recombinant human Peroxisomal biogenesis factor 19 protein (1-299AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

32 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5824( Human), Entrez Gene:19298( Mouse), Entrez Gene:289233( Rat), Omim:600279( Human), SwissProt:P40855( Human), SwissProt:Q8VCI5( Mouse), SwissProt:Q9QYU1( Rat), Unigene:517232( Human), Unigene:247764( Mouse), Unigene:203104( Rat), Unigene:225447( Rat)

Protein function

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. .

Protein tissue specificity

Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form. .

Involvement in disease

Peroxisome biogenesis disorder complementation group 14 (PBD-CG14) [MIM:614886]: A peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS). . Note=The disease is caused by mutations affecting the gene represented in this entry.; Peroxisome biogenesis disorder 12A (PBD12A) [MIM:614886]: A fatal peroxisome biogenesis disorder belonging to the Zellweger disease spectrum and clinically characterized by severe neurologic dysfunction with profound psychomotor retardation, severe hypotonia and neonatal seizures, craniofacial abnormalities, liver dysfunction, and biochemically by the absence of peroxisomes. Additional features include cardiovascular and skeletal defects, renal cysts, ocular abnormalities, and hearing impairment. Most severely affected individuals with the classic form of the disease (classic Zellweger syndrome) die within the first year of life. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peroxin-19 family.

Protein cellular localization

Cytoplasm . Peroxisome membrane ; Lipid-anchor ; Cytoplasmic side . Note=Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes. .

Research area

All research areas>Signaling Intermediates>Peroxin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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