Anti-PHKB Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-PHKB Antibody (CSB-PA849977ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Phosphorylase b kinase regulatory subunit beta Antibody,Phosphorylase kinase subunit beta Antibody,PHKB Antibody

More alternative names for the antibody
DKFZp781E15103 antibody|FLJ41698 antibody|KPBB_HUMAN antibody|PHKB antibody|Phosphorylase b kinase regulatory subunit beta antibody|Phosphorylase kinase B antibody|Phosphorylase kinase beta polypeptide antibody|Phosphorylase kinase beta subunit antibody|Phosphorylase kinase subunit beta antibody
Anti-Phosphorylase B antibody (ab208930)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-PHKB Antibody

Catalogue No.

CSB-PA849977ESR2HU

Reactivity

Human

Immunogen

Recombinant human Phosphorylase b kinase regulatory subunit beta protein (854-1093AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

124 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:5257( Human), Entrez Gene:102093( Mouse), Entrez Gene:361377( Rat), Omim:172490( Human), SwissProt:Q93100( Human), SwissProt:Q7TSH2( Mouse), Unigene:78060( Human), Unigene:237296( Mouse), Unigene:6488( Rat)

Protein function

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.

Involvement in disease

Glycogen storage disease 9B (GSD9B) [MIM:261750]: A metabolic disorder characterized by hepatomegaly, only slightly elevated transaminases and plasma lipids, clinical improvement with increasing age, and remarkably no clinical muscle involvement. Biochemical observations suggest that this mild phenotype is caused by an incomplete holoenzyme that lacks the beta subunit, but that may possess residual activity. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the phosphorylase b kinase regulatory chain family.

Protein post-translational modifications

Ser-701 is probably phosphorylated by PKA.; Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated. .

Protein cellular localization

Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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